Molecular cloning and characterization of UDP-glucose dehydrogenase from the amphibian Xenopus laevis and its involvement in hyaluronan synthesis.
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Regulated Hyaluronan Synthesis by Vascular CellsRegulation of hyaluronan synthesis in vascular diseases and diabetesOxidative Stress and Metabolic Perturbations in Wooden Breast Disorder in ChickensHyaluronan expressed by the hematopoietic microenvironment is required for bone marrow hematopoiesis.CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention.Molecular and genetic analyses of the putative Proteus O antigen gene locus.Natural antisense transcript for hyaluronan synthase 2 (HAS2-AS1) induces transcription of HAS2 via protein O-GlcNAcylation.Hyaluronan and human endothelial cell behavior.Divergent Sp1 protein levels may underlie differential expression of UDP-glucose dehydrogenase by fibroblasts: role in susceptibility to orbital Graves disease.Molecular cloning of a novel glucuronokinase/putative pyrophosphorylase from zebrafish acting in an UDP-glucuronic acid salvage pathway4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer.Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1.UDP-glucose dehydrogenase polymorphisms from patients with congenital heart valve defects disrupt enzyme stability and quaternary assembly.4-Methylumbelliferone Diminishes Catabolically Activated Articular Chondrocytes and Cartilage Explants via a Mechanism Independent of Hyaluronan Inhibition.Epigenetics in extracellular matrix remodeling and hyaluronan metabolism.Hyaluronan in cytosol--microinjection-based probing of its existence and suggested functions.Hyaluronan synthase 1: a mysterious enzyme with unexpected functionsBiology and biotechnology of hyaluronan.Glycosaminoglycans and glucose prevent apoptosis in 4-methylumbelliferone-treated human aortic smooth muscle cellsBrain extracellular space, hyaluronan, and the prevention of epileptic seizures.Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis.MDA-MB-231 breast cancer cell viability, motility and matrix adhesion are regulated by a complex interplay of heparan sulfate, chondroitin-/dermatan sulfate and hyaluronan biosynthesis.Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase.Role of UDP-N-acetylglucosamine (GlcNAc) and O-GlcNAcylation of hyaluronan synthase 2 in the control of chondroitin sulfate and hyaluronan synthesis.Hyaluronan synthesis is inhibited by adenosine monophosphate-activated protein kinase through the regulation of HAS2 activity in human aortic smooth muscle cells.Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and DifferentiationModulation of hyaluronan synthase activity in cellular membrane fractions.Androgen-stimulated UDP-glucose dehydrogenase expression limits prostate androgen availability without impacting hyaluronan levels.Inhibitory effects of gallic acid and quercetin on UDP-glucose dehydrogenase activity.Genetic diversity of the O antigens of Proteus species and the development of a suspension array for molecular serotyping.Hyaluronan based hydrogels provide an improved model to study megakaryocyte-matrix interactionsMannose reduces hyaluronan and leukocytes in wound granulation tissue and inhibits migration and hyaluronan-dependent monocyte binding.Signal pathways regulating hyaluronan secretion into static and cycled synovial joints of rabbits.Mechanosensitive hyaluronan secretion: stimulus-response curves and role of transcription-translation-translocation in rabbit joints.Molecular control of the hyaluronan biosynthesis.Mannose inhibits hyaluronan synthesis by down-regulation of the cellular pool of UDP-N-acetylhexosamines.Chromosomal integration of hyaluronic acid synthesis (has) genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis.Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactis.Regulation of UDP-glucose dehydrogenase is sufficient to modulate hyaluronan production and release, control sulfated GAG synthesis, and promote chondrogenesis.Abstracts of the XXVII Italian Society for the Study of Connective Tissues (SISC) Meeting, Bologna, Italy, 8-10 November 2007
P2860
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P2860
Molecular cloning and characterization of UDP-glucose dehydrogenase from the amphibian Xenopus laevis and its involvement in hyaluronan synthesis.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@en
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@nl
type
label
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@en
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@nl
prefLabel
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@en
Molecular cloning and characte ...... ement in hyaluronan synthesis.
@nl
P2093
P2860
P50
P356
P1476
Molecular cloning and characte ...... vement in hyaluronan synthesis
@en
P2093
Anna Genasetti
Eugenia Karousou
Giancarlo De Luca
Irma Nardi
Manuela Rizzi
Manuela Viola
Vincent C Hascall
P2860
P304
P356
10.1074/JBC.M508516200
P407
P577
2006-01-17T00:00:00Z