about
Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2Impaired pressure-induced constriction in mouse middle cerebral arteries of ASIC2 knockout miceChronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.Chronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle.Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle.Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen speciesChronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstrictionASIC proteins regulate smooth muscle cell migration.Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia.Sensing tension: epithelial sodium channel/acid-sensing ion channel proteins in cardiovascular homeostasis.ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cellsPICK1/calcineurin suppress ASIC1-mediated Ca2+ entry in rat pulmonary arterial smooth muscle cells.ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.Angiotensin II regulation of renal vascular ENaC proteinsRole of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension.Calcium homeostasis and sensitization in pulmonary arterial smooth muscle.Smooth muscle acid-sensing ion channel 1: pathophysiological implication in hypoxic pulmonary hypertension.Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertensionEnhanced NO-dependent pulmonary vasodilation limits increased vasoconstrictor sensitivity in neonatal chronic hypoxia.Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation.Pulmonary PKG-1 is upregulated following chronic hypoxia.Contribution of oxygen radicals to altered NO-dependent pulmonary vasodilation in acute and chronic hypoxia.Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia.Chronic hypoxia augments protein kinase G-mediated Ca2+ desensitization in pulmonary vascular smooth muscle through inhibition of RhoA/Rho kinase signaling.Vascular ENaC proteins are required for renal myogenic constriction.Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle after chronic hypoxia.Dietary salt enhances benzamil-sensitive component of myogenic constriction in mesenteric arteries.Renal vascular responses to CORM-A1 in the mouse.RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia.Reduced membrane cholesterol limits pulmonary endothelial Ca2+ entry after chronic hypoxia.Reduced membrane cholesterol after chronic hypoxia limits Orai1-mediated pulmonary endothelial Ca2+ entry.Actin Polymerization Contributes to Enhanced Pulmonary Vasoconstrictor Reactivity Following Chronic Hypoxia.Role of acid-sensing ion channels in hypoxia- and hypercapnia-induced ventilatory responses.Cholesterol Regulation of Pulmonary Endothelial Calcium HomeostasisMyogenic vasoconstriction in mouse renal interlobar arteries: role of endogenous beta and gammaENaCInterleukin-6 trans-signaling contributes to chronic hypoxia-induced pulmonary hypertensionRedox Regulation of Ion Channels and Receptors in Pulmonary HypertensionPKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal ratsLoss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Nikki Jernigan
@ast
Nikki Jernigan
@en
Nikki Jernigan
@es
Nikki Jernigan
@nl
Nikki Jernigan
@sl
type
label
Nikki Jernigan
@ast
Nikki Jernigan
@en
Nikki Jernigan
@es
Nikki Jernigan
@nl
Nikki Jernigan
@sl
prefLabel
Nikki Jernigan
@ast
Nikki Jernigan
@en
Nikki Jernigan
@es
Nikki Jernigan
@nl
Nikki Jernigan
@sl
P106
P1153
6602779149
P31
P496
0000-0001-6269-2274