Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.
about
Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2Aging-associated oxidative stress leads to decrease in IAS tone via RhoA/ROCK downregulationExposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxideChronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle.Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle.Endothelin-1 contributes to increased NFATc3 activation by chronic hypoxia in pulmonary arteries.Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen speciesRole for PKCβ in enhanced endothelin-1-induced pulmonary vasoconstrictor reactivity following intermittent hypoxiaIntermittent hypoxia in rats increases myogenic tone through loss of hydrogen sulfide activation of large-conductance Ca(2+)-activated potassium channels.Depolarization-dependent contraction increase after birth and preservation following long-term hypoxia in sheep pulmonary arteriesPredicted effects of nitric oxide and superoxide on the vasoactivity of the afferent arteriole.Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery.Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension.Effects of angiotensin II on the cerebral circulation: role of oxidative stress.Reactive oxygen species and antioxidants in pulmonary hypertension.mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects.NFAT is required for spontaneous pulmonary hypertension in superoxide dismutase 1 knockout mice.Tissue protection and endothelial cell signaling by 20-HETE analogs in intact ex vivo lung slices.Reactive oxygen species in pulmonary vascular remodeling.Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding.Reactive oxygen species as therapeutic targets in pulmonary hypertension.Calcium homeostasis and sensitization in pulmonary arterial smooth muscle.Rho GTPases in the regulation of pulmonary vascular barrier function.Hypoxia and the modulation of the actin cytoskeleton - emerging interrelations.Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertensionRole of hypoxia-induced transglutaminase 2 in pulmonary artery smooth muscle cell proliferation.Endothelial Cell Reactive Oxygen Species and Ca2+ Signaling in Pulmonary Hypertension.Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension.Long-Term High Altitude Hypoxia influences Pulmonary Arterial L-type Calcium Channel mediated Ca(2+) signals and Contraction in Fetal and Adult Sheep.RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia.PLCγ1-PKCε-IP3R1 plays an important role in hypoxia-induced calcium response in pulmonary artery smooth muscle cells.Actin Polymerization Contributes to Enhanced Pulmonary Vasoconstrictor Reactivity Following Chronic Hypoxia.Role of Rho-kinase signaling and endothelial dysfunction in modulating blood flow distribution in pulmonary hypertension.Pulmonary Hypertension Is a Probable NO/ONOO− Cycle Disease: A Review
P2860
Q28582157-3054D01E-9437-46F2-85B2-8B9FBA91049DQ33701581-6D365FD0-D9BC-48D2-A7AC-9062CC0DD1E9Q34062951-FAA1DB79-A2E0-4802-B91C-8190D63F90EBQ34131753-88D55FB0-3F64-4328-A74E-A6BE27563196Q34519078-C8016FCC-5EFB-4741-8B09-2F52DF52205FQ35159459-6E1A6A52-535C-4459-9276-14CFEC9D48C0Q35325870-A6B998A0-9210-44A8-8572-572C5A4305BCQ35543602-8DA36070-EA0B-4989-A267-F79EBDBAEDA3Q35604743-B918A11E-B684-4AC0-AB19-49AAFEAF8FA0Q35929755-53CF1592-FD96-44C8-85E2-30C2E00ED2B5Q36174482-32775C48-B419-4110-ABB1-825BA2A251F1Q36185490-CAD94B82-7AD4-40BB-AE9D-3C775BA5C118Q36494495-DB0BE3AF-C551-4B89-A61E-2C37BAAD062FQ36516761-7F1A7022-B18F-43C7-B00F-A028285EB2CEQ36747034-3F32ABB5-FB9C-41A7-A9E7-0879647E8BB8Q36788720-4C5042D0-400B-4463-BCCE-E1CC7AD94E1AQ36837739-D017B831-9F36-4800-B98A-4B1B69209D56Q37109816-6F9DFC07-A8F6-4C0C-AD38-E5EA96DEA0CDQ37532988-AEE6741D-E593-49DE-AB81-DA1A7F3E9E65Q37635880-ADE2468B-2FE5-4623-9CF4-CB6290E8A5E2Q38074770-353B6194-D4CE-4014-941E-7ED79FDE6C63Q38151917-824FEB2B-050B-4623-AD04-48C4F9D8894BQ38193703-4F4F8B54-3A06-45B0-86D5-3BA39B862620Q38989120-6225E453-7610-4902-AA93-459CD313A76AQ40987019-E7E0BEF8-33F8-4CD1-8CE0-9EA14558FBC4Q42547773-13BE9941-7888-43E1-ACFE-1449181DEFD9Q46280838-F9617E60-0CBE-4806-9864-2597F45894A0Q46280877-EE3D54DA-6A5E-44F9-B6B2-D4BA784B922AQ46671705-0DA1856C-15C8-4864-A412-394518F163D0Q47603839-10A7C426-2A4D-49C9-9098-32539FC4313AQ49502020-F6432CAB-FB80-465B-8F7C-1BAC0DD2B6BAQ49663303-AEEC8EF6-B32E-40C9-9800-ACA235E889BFQ54621877-5157AF78-0297-49E0-AF24-9BA158A0B1FBQ58998388-9D6BE2E9-FCE3-4D92-8CF4-CF1F87BBEE42
P2860
Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.
description
2009 nî lūn-bûn
@nan
2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@ast
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@en
type
label
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@ast
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@en
prefLabel
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@ast
Chronic hypoxia augments depol ...... dependent stimulation of RhoA.
@en
P2093
P2860
P1476
Chronic hypoxia augments depol ...... -dependent stimulation of RhoA
@en
P2093
Benjimen R Walker
Brad R S Broughton
Charles E Norton
Thomas C Resta
P2860
P304
P356
10.1152/AJPLUNG.00276.2009
P577
2009-11-06T00:00:00Z