Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.
about
Distinct and Shared Determinants of Cardiomyocyte Contractility in Multi-Lineage Competent Ethnically Diverse Human iPSCs.Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in miceSystematic mapping of functional enhancer-promoter connections with CRISPR interference.CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome.Hierarchy within the mammary STAT5-driven Wap super-enhancer.Genetic dissection of the α-globin super-enhancer in vivo.Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations.The GATA factor revolution in hematology.Epo reprograms the epigenome of erythroid cells.BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire.CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.CRISPR: express delivery to any DNA address.Enhancers and their dynamics during hematopoietic differentiation and emerging strategies for therapeutic action.Genome-Wide Approaches to Defining Macrophage Identity and FunctionRoles of the RUNX1 Enhancer in Normal Hematopoiesis and Leukemogenesis.Functional Enhancers As Master Regulators of Tissue-Specific Gene Regulation and Cancer Development.Transcriptional response to stress is pre-wired by promoter and enhancer architectureThe LDB1 Complex Co-opts CTCF for Erythroid Lineage-Specific Long-Range Enhancer Interactions.MyoD- and FoxO3-mediated hotspot interaction orchestrates super-enhancer activity during myogenic differentiation.Super-Enhancers at the Nanog Locus Differentially Regulate Neighboring Pluripotency-Associated Genes.Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes.Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation.Multiple enhancer regions govern the transcription of CCN2 during embryonic development.Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications.CRISPR-based strategies for studying regulatory elements and chromatin structure in mammalian gene control.Comparative analysis of three-dimensional chromosomal architecture identifies a novel fetal hemoglobin regulatory element.Maternal obesity and increased neonatal adiposity correspond with altered infant mesenchymal stem cell metabolism.Intracellular iron and heme trafficking and metabolism in developing erythroblasts.Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements.Concise Review: Advanced Cell Culture Models for Diamond Blackfan Anemia and Other Erythroid Disorders.The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries.Integrative view on how erythropoietin signaling controls transcription patterns in erythroid cells.Genomic dissection of enhancers uncovers principles of combinatorial regulation and cell type-specific wiring of enhancer-promoter contacts.Nanog Expression in Embryonic Stem Cells - An Ideal Model System to Dissect Enhancer Function.Regulation of embryonic haematopoietic multipotency by EZH1.Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.Transcription factor-dependent 'anti-repressive' mammalian enhancers exclude H3K27me3 from extended genomic domains.Exploiting genetic variation to uncover rules of transcription factor binding and chromatin accessibility.Dissecting super-enhancer hierarchy based on chromatin interactions.Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
P2860
Q30830783-B9AB95B7-59FB-4F89-AA94-31A90E81C45EQ33635936-7297EAA3-ED28-4149-B5D0-5072D761F704Q33709312-ABE51AB3-93DD-437F-B1BC-4A3265472276Q33766701-ECF2B21D-EC20-4680-A8DC-7C8C0744AECEQ37131577-C3422EE2-4D5D-42A6-A92B-95DC897C8AA8Q37327013-DEBDFD17-73CC-4E42-A903-AF8AED36FE46Q37496355-F8B795C2-AC59-4343-AFD6-8C0DFB4D36DBQ38558334-A5722D71-6AAC-4387-9170-12512AA1245DQ38730271-CA7343B5-B1BC-470A-972F-0F5886C1923DQ38744593-8A2E04AF-A41C-46A6-A872-8F5C99961E7FQ38766859-70DD94B6-8C91-4683-AB66-FFA7AD3EF2FEQ38797121-A3CD0114-A62F-411B-8C1D-93DAF76A460DQ38958989-F13ACE87-485E-4092-9A52-DBF7697F2005Q39088450-8AFA4496-2ACB-4FB8-8413-A747857F297DQ39181412-838F131E-F32A-4EED-8BEC-46E5CAB0A832Q39209007-87AD0697-B3A2-420A-A427-49E2A3A029D8Q41422876-92E11D86-BAF1-43BD-A155-C706C91C1EF2Q41469298-CFB0250B-527B-4F41-BD3C-F6541B32A707Q41627960-59EC87C5-7E75-471E-BED1-9A017CBDE755Q42111356-9BA27184-D6BA-4050-856C-A920DDF2B552Q42324921-E91D7AD1-FE2E-409D-AB8C-401605E09B60Q45984129-F0FD6F43-DCDD-420A-B0CA-58243B857EB4Q46236843-2F072396-906F-4AED-A7D9-A1BE86FC1527Q47147613-162F5CD9-25DC-4002-8E66-9E6C3DFA94ECQ47291540-BA2D2354-9B51-41A2-B574-AC8EB6B787E8Q47668925-2037642C-4ABE-401B-8EDD-5C7AFEDF1FACQ47673849-E11E6FFA-EA61-4BD7-9E95-80B3A212C13CQ47969812-D2BFF2DE-9C0C-47BB-9F50-962AF4754FB8Q48222935-B92589F5-52AE-4001-9920-BA603BA506CDQ48327578-50F82DA2-8C84-4F67-941F-8D44798BEF4CQ49484906-7D633A6F-48E7-4415-8333-E37FCB80C075Q49491478-AE2D2E0C-C4B4-4089-A2C5-440130C16582Q49552110-FE194352-7207-49F0-8D2B-CB41A5D6163BQ49606480-E086C863-A772-42F1-AE93-C3437808FE23Q50001698-9D3DF46E-FB4A-4770-B688-3EA8FA5B5265Q50041523-38A9103C-17C6-4FB4-BA9E-AAAAF66FE268Q50102218-BC6E8118-BEE7-4484-98AF-7B515692CC60Q50302255-50CB0C3C-CF80-48E4-9FB4-538500601DE0Q51418242-A9F442F9-1675-4EC0-B66C-72E548892EDBQ52690497-82A9A925-CD7D-42F6-BB46-F17EF3FF87A2
P2860
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@en
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@nl
type
label
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@en
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@nl
prefLabel
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@en
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@nl
P2093
P2860
P1433
P1476
Dynamic Control of Enhancer Re ...... cription during Hematopoiesis.
@en
P2093
Guo-Cheng Yuan
Jialiang Huang
Leonard I Zon
Stuart H Orkin
Teresa V Bowman
Yuannyu Zhang
P2860
P356
10.1016/J.DEVCEL.2015.12.014
P407
P577
2016-01-01T00:00:00Z