beta-Cells step up in controlling the autoimmune response.

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PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.

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beta-Cells step up in controlling the autoimmune response.

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2010 nî lūn-bûn

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2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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2010年论文

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beta-Cells step up in controlling the autoimmune response.

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beta-Cells step up in controlling the autoimmune response.

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beta-Cells step up in controlling the autoimmune response.

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beta-Cells step up in controlling the autoimmune response.

@nl

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beta-Cells step up in controlling the autoimmune response.

@en

beta-Cells step up in controlling the autoimmune response.

@nl

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beta-Cells step up in controlling the autoimmune response.

@en

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The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to beta cell damage

Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells.

T-cell costimulatory pathways in allograft rejection and tolerance.

Tissue expression of PD-L1 mediates peripheral T cell tolerance.

Selective delivery of beta cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8+ T cells in NOD mice.

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event

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1861-1864

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scholarly article

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10.2337/DB10-0662

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English

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Paolo Fiorina

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2010-08-01T00:00:00Z

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45406663

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20668291

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2911052

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beta-Cells step up in controlling the autoimmune response.

about

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P2860

beta-Cells step up in controlling the autoimmune response.

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