Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process. - Wikidata - awgldk - TriplyDB

Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.

Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.

http://www.wikidata.org/entity/Q42685258

about

Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.Sensitive Versatile Fluorogenic Transmembrane Peptide Substrates for Rhomboid Intramembrane Proteases.Nicastrin functions to sterically hinder γ-secretase-substrate interactions driven by substrate transmembrane domain Nicastrin guards Alzheimer's gate Crystal Structures and Inhibition Kinetics Reveal a Two-Stage Catalytic Mechanism with Drug Design Implications for Rhomboid Proteolysis An Inducible Reconstitution System for the Real-Time Kinetic Analysis of Protease Activity and Inhibition Inside the Membrane.Enzymatic Assays for Studying Intramembrane Proteolysis.Structural insights into adiponectin receptors suggest ceramidase activity.Both positional and chemical variables control in vitro proteolytic cleavage of a presenilin ortholog.Involvement of a conserved GFG motif region in substrate binding by RseP, an Escherichia coli S2P protease.Bacillus subtilis Intramembrane Protease RasP Activity in Escherichia coli and In Vitro.Membrane properties that shape the evolution of membrane enzymes.

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P2860

Intramembrane proteolysis of β-amyloid precursor protein by γ-secretase is an unusually slow process.

http://www.wikidata.org/entity/Q42685258

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2015 nî lūn-bûn

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2015年の論文

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Intramembrane proteolysis of β ...... is an unusually slow process.

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Intramembrane proteolysis of β ...... is an unusually slow process.

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Intramembrane proteolysis of β ...... is an unusually slow process.

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J.BPJ.2014.12.045

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Intramembrane proteolysis of β ...... is an unusually slow process.

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Amelie Ebke

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Edith Winkler

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Frits Kamp

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Harald Steiner

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Johannes Trambauer

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P2860

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin

Purification and characterization of the human gamma-secretase complex

Membrane lipids: where they are and how they behave

Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1

Proteolysis inside the Membrane Is a Rate-Governed Reaction Not Driven by Substrate Affinity

Trafficking and proteolytic processing of APP

Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway

Gamma-secretase complex assembly within the early secretory pathway

Subcellular organelle lipidomics in TLR-4-activated macrophages

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