External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.
about
Epithelial Na(+) channel regulation by cytoplasmic and extracellular factorsConserved charged residues at the surface and interface of epithelial sodium channel subunits--roles in cell surface expression and the sodium self-inhibition responseAmiloride-sensitive sodium absorption is different in vertebrates and invertebrates.Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines.Extracellular allosteric regulatory subdomain within the gamma subunit of the epithelial Na+ channel.Effects of pH buffering on horizontal and ganglion cell light responses in primate retina: evidence for the proton hypothesis of surround formationCpt-cAMP activates human epithelial sodium channels via relieving self-inhibitionExternal Cu2+ inhibits human epithelial Na+ channels by binding at a subunit interface of extracellular domains.8-(4-chlorophenylthio)-guanosine-3',5'-cyclic monophosphate-Na stimulates human alveolar fluid clearance by releasing external Na+ self-inhibition of epithelial Na+ channelsCharacterization of a novel splice variant of δ ENaC subunit in human lungs.Probing the structural basis of Zn2+ regulation of the epithelial Na+ channel.Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool.Gain-of-function variant of the human epithelial sodium channel.Extracellular protons regulate human ENaC by modulating Na+ self-inhibitionExtracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targetsSARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoformsASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.Extracellular chloride regulates the epithelial sodium channel.Deletion of α-subunit exon 11 of the epithelial Na+ channel reveals a regulatory moduleEpithelial Sodium Channel ENaC is a Modifier of the Long Term Non-progressive Phenotype Associated with F508del CFTR Mutations.Effect of divalent heavy metals on epithelial Na+ channels in A6 cells.Nickel and extracellular acidification inhibit the water permeability of human aquaporin-3 in lung epithelial cells.Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesiumNickel toxicity in embryos and larvae of the South American toad: effects on cell differentiation, morphogenesis, and oxygen consumption.Novel determinants of epithelial sodium channel gating within extracellular thumb domains.Characterization of an amiloride binding region in the alpha-subunit of ENaC.Mutations in the pore region modify epithelial sodium channel gating by shear stress.C termini of the Escherichia coli mechanosensitive ion channel (MscS) move apart upon the channel opening.Multiple epithelial Na+ channel domains participate in subunit assembly.Extracellular histidine residues crucial for Na+ self-inhibition of epithelial Na+ channels.On the interaction between amiloride and its putative alpha-subunit epithelial Na+ channel binding site.Opposite effects of Ni2+ on Xenopus and rat ENaCs expressed in Xenopus oocytes.Functional role of extracellular loop cysteine residues of the epithelial Na+ channel in Na+ self-inhibition.Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.Distinct structural elements in the first membrane-spanning segment of the epithelial sodium channel.
P2860
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P2860
External nickel inhibits epithelial sodium channel by binding to histidine residues within the extracellular domains of alpha and gamma subunits and reducing channel open probability.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
External nickel inhibits epith ...... cing channel open probability.
@en
External nickel inhibits epith ...... cing channel open probability.
@nl
type
label
External nickel inhibits epith ...... cing channel open probability.
@en
External nickel inhibits epith ...... cing channel open probability.
@nl
prefLabel
External nickel inhibits epith ...... cing channel open probability.
@en
External nickel inhibits epith ...... cing channel open probability.
@nl
P2860
P356
P1476
External nickel inhibits epith ...... cing channel open probability.
@en
P2093
Clint J Perry
Thomas R Kleyman
P2860
P304
50098-50111
P356
10.1074/JBC.M209975200
P407
P50
P577
2002-10-22T00:00:00Z