Orphan receptor small heterodimer partner suppresses tumorigenesis by modulating cyclin D1 expression and cellular proliferation.
about
An autoregulatory feedback loop between Mdm2 and SHP that fine tunes Mdm2 and SHP stabilityEndocrine fibroblast growth factors 15/19 and 21: from feast to famineTranscriptional mechanism for the paired miR-433 and miR-127 genes by nuclear receptors SHP and ERRgammaBile Acid Metabolism and Signaling in Cholestasis, Inflammation, and CancerNuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Hepatic signaling by the mechanistic target of rapamycin complex 2 (mTORC2)The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptorsNuclear receptor expression defines a set of prognostic biomarkers for lung cancerRole of nuclear receptor SHP in metabolism and cancer.Nuclear receptor SHP activates miR-206 expression via a cascade dual inhibitory mechanism.The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.Small heterodimer partner overexpression partially protects against liver tumor development in farnesoid X receptor knockout mice.Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth.Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration.Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice.Overexpression of nuclear receptor SHP in adipose tissues affects diet-induced obesity and adaptive thermogenesisSodium taurocholate inhibits intestinal adenoma formation in APCMin/+ mice, potentially through activation of the farnesoid X receptorFarnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner.Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.Farnesoid X receptor inhibits LNcaP cell proliferation via the upregulation of PTENLoss of the orphan nuclear receptor SHP is more pronounced in fibrolamellar carcinoma than in typical hepatocellular carcinoma.Cross-regulation of protein stability by p53 and nuclear receptor SHP.FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model.Bile acid signaling and liver regeneration.A feedback inhibition between miRNA-127 and TGFβ/c-Jun cascade in HCC cell migration via MMP13Characterization of the mitochondrial localization of the nuclear receptor SHP and regulation of its subcellular distribution by interaction with Bcl2 and HNF4α.Small heterodimer partner/neuronal PAS domain protein 2 axis regulates the oscillation of liver lipid metabolism.Nuclear receptor SHP inhibition of Dnmt1 expression via ERRγ.Tumor suppressor p53 regulates bile acid homeostasis via small heterodimer partner.Cytoplasmic tyrosine phosphatase Shp2 coordinates hepatic regulation of bile acid and FGF15/19 signaling to repress bile acid synthesis.Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinomaLoss of FXR protects against diet-induced obesity and accelerates liver carcinogenesis in ob/ob mice.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Zinc-induced Dnmt1 expression involves antagonism between MTF-1 and nuclear receptor SHP.FXR and liver carcinogenesisNew Insights into Orphan Nuclear Receptor SHP in Liver CancerSRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.Downregulation of nuclear receptor FXR is associated with multiple malignant clinicopathological characteristics in human hepatocellular carcinoma.Nuclear receptors as drug targets in cholestatic liver diseases.Genome-wide transcriptome analysis identifies novel gene signatures implicated in human chronic liver disease
P2860
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P2860
Orphan receptor small heterodimer partner suppresses tumorigenesis by modulating cyclin D1 expression and cellular proliferation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Orphan receptor small heterodi ...... on and cellular proliferation.
@en
Orphan receptor small heterodi ...... on and cellular proliferation.
@nl
type
label
Orphan receptor small heterodi ...... on and cellular proliferation.
@en
Orphan receptor small heterodi ...... on and cellular proliferation.
@nl
prefLabel
Orphan receptor small heterodi ...... on and cellular proliferation.
@en
Orphan receptor small heterodi ...... on and cellular proliferation.
@nl
P2093
P2860
P356
P1433
P1476
Orphan receptor small heterodi ...... on and cellular proliferation.
@en
P2093
David D Moore
Kyungtae Park
Yunhee Choi
Yuxia Zhang
P2860
P304
P356
10.1002/HEP.22342
P407
P577
2008-07-01T00:00:00Z