Avidity determines T-cell reactivity in abacavir hypersensitivity. - Wikidata - awgldk - TriplyDB

Avidity determines T-cell reactivity in abacavir hypersensitivity.

Avidity determines T-cell reactivity in abacavir hypersensitivity.

http://www.wikidata.org/entity/Q42718095

about

T-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevance Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.Idiosyncratic adverse drug reactions: current concepts Immediate-type hypersensitivity drug reactions Abacavir pharmacogenetics--from initial reports to standard of care Drug allergy: causes and desensitization Abacavir induced T cell reactivity from drug naïve individuals shares features of allo-immune responses Abacavir-reactive memory T cells are present in drug naïve individuals Genotyping for severe drug hypersensitivity.A novel rapid (20-minute) IL-6 release assay using blood mononuclear cells of patients with various clinical forms of drug induced skin injuries HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects.HLA and pharmacogenetics of drug hypersensitivity.Are drug metabolites able to cause T-cell-mediated hypersensitivity reactions?Clinical Role of Human Leukocyte Antigen in Health and Disease.Structural Elements Recognized by Abacavir-Induced T Cells.The role of HLA genes in pharmacogenomics: unravelling HLA associated adverse drug reactions.Novel Concepts for Drug Hypersensitivity Based on the Use of Long-Time Scale Molecular Dynamic Simulation.Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome.HLAs: Key regulators of T-cell-mediated drug hypersensitivity.Elevated levels of the antimicrobial peptide LL-37 in hidradenitis suppurativa are associated with a Th1/Th17 immune response.Detection of Primary T Cell Responses to Drugs and Chemicals in HLA-Typed Volunteers: Implications for the Prediction of Drug Immunogenicity.Peptide binding specificities of HLA-B*5701 and B*5801.Pharmacogenomic Advances in the Prediction and Prevention of Cutaneous Idiosyncratic Drug Reactions.Explanation for HLA-B*57:01-linked immune-mediated abacavir-induced hypersensitivity.A transgenic mouse model for HLA-B*57:01-linked abacavir drug tolerance and reactivity.Allopurinol hypersensitivity is primarily mediated by dose-dependent oxypurinol-specific T cell response.

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P2860

Avidity determines T-cell reactivity in abacavir hypersensitivity.

http://www.wikidata.org/entity/Q42718095

description

2012 nî lūn-bûn

@nan

2012年の論文

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2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@en

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@nl

type

label

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@en

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@nl

prefLabel

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@en

Avidity determines T-cell reactivity in abacavir hypersensitivity.

@nl

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P1433

European Journal of Immunology

P1476

Avidity determines T-cell reactivity in abacavir hypersensitivity

@en

P2093

Benno Schnyder

http://www.w3.org/2001/XMLSchema#string

Daniel Yerly

http://www.w3.org/2001/XMLSchema#string

Jacqueline Adam

http://www.w3.org/2001/XMLSchema#string

Klara K Eriksson

http://www.w3.org/2001/XMLSchema#string

Stefano Fontana

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P2860

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome

Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity

Optimization of the MHC class I peptide cargo is dependent on tapasin

Medical genetics: a marker for Stevens-Johnson syndrome

A European study of HLA-B in Stevens-Johnson syndrome and toxic epidermal necrolysis related to five high-risk drugs

The metabolic activation of abacavir by human liver cytosol and expressed human alcohol dehydrogenase isozymes

HLA-B*1502-bound peptides: implications for the pathogenesis of carbamazepine-induced Stevens-Johnson syndrome.

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.

Metabolic activation in drug allergies.

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1706-1716

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scholarly article

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10.1002/EJI.201142159

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7

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42

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Werner J. Pichler

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2012-06-14T00:00:00Z

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224958259

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22585534

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