Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome
about
Molecular docking as a popular tool in drug design, an in silico travelT-cell-mediated drug hypersensitivity: immune mechanisms and their clinical relevanceBiomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory scienceStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewDrug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoireIdentifying unexpected therapeutic targets via chemical-protein interactomeBinding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurementsA structure-based approach for mapping adverse drug reactions to the perturbation of underlying biological pathwaysExploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case studySystematic drug repositioning based on clinical side-effectsPrediction of drug-target interactions for drug repositioning only based on genomic expression similarityAdverse drug reaction prediction using scores produced by large-scale drug-protein target docking on high-performance computing machinesDeciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin ActionDPDR-CPI, a server that predicts Drug Positioning and Drug Repositioning via Chemical-Protein InteractomeSystematic identification of proteins that elicit drug side effectsDDI-CPI, a server that predicts drug-drug interactions through implementing the chemical-protein interactome.DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical-protein interactomeRole of systems pharmacology in understanding drug adverse events.Abacavir induces loading of novel self-peptides into HLA-B*57: 01: an autoimmune model for HLA-associated drug hypersensitivity.Structure-based systems biology for analyzing off-target bindingDelayed drug hypersensitivity: models of T-cell stimulationAdvanced systems biology methods in drug discovery and translational biomedicineLarge-scale identification of adverse drug reaction-related proteins through a random walk model.Chemical-protein interactome and its application in off-target identification.Drug repositioning for orphan diseases.Studies on abacavir-induced hypersensitivity reaction: a successful example of translation of pharmacogenetics to personalized medicine.Identification of drug targets related to the induction of ventricular tachyarrhythmia through a systems chemical biology approach.Inferring Chemogenomic Features from Drug-Target Interaction Networks.Benchmarking a Wide Range of Chemical Descriptors for Drug-Target Interaction Prediction Using a Chemogenomic Approach.HLADR: a database system for enhancing the discovery of biomarkers for predicting human leukocyte antigen-mediated idiosyncratic adverse drug reactions.Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach.Identification of chemogenomic features from drug-target interaction networks using interpretable classifiers.Avidity determines T-cell reactivity in abacavir hypersensitivity.Can sodium/hydrogen exchange inhibitors be repositioned for treating attention deficit hyperactivity disorder? An in silico approach.RepurposeVS: A Drug Repurposing-Focused Computational Method for Accurate Drug-Target Signature Predictions.Drug Induced Hypersensitivity and the HLA Complex.A Practical Estimation Method for Analyzing Adverse Drug Reactions Using Data MiningCritical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions
P2860
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P2860
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Harvesting candidate genes res ...... a chemical-protein interactome
@ast
Harvesting candidate genes res ...... a chemical-protein interactome
@en
Harvesting candidate genes res ...... a chemical-protein interactome
@nl
type
label
Harvesting candidate genes res ...... a chemical-protein interactome
@ast
Harvesting candidate genes res ...... a chemical-protein interactome
@en
Harvesting candidate genes res ...... a chemical-protein interactome
@nl
prefLabel
Harvesting candidate genes res ...... a chemical-protein interactome
@ast
Harvesting candidate genes res ...... a chemical-protein interactome
@en
Harvesting candidate genes res ...... a chemical-protein interactome
@nl
P2093
P2860
P3181
P1476
Harvesting candidate genes res ...... a chemical-protein interactome
@en
P2093
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1000441
P407
P577
2009-07-01T00:00:00Z