Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.
about
The Ews-ERG fusion protein can initiate neoplasia from lineage-committed haematopoietic cells.The CRISPR revolution and its impact on cancer researchHijacked in cancer: the KMT2 (MLL) family of methyltransferasesAnimal models of leukemia: any closer to the real thing?Extensions of MADM (mosaic analysis with double markers) in miceModeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organizationEfficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates.Murine models of acute leukemia: important tools in current pediatric leukemia research.Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesisModeling cancer in mice.MLL fusions: pathways to leukemiaDeveloping genetically engineered mouse models to study tumor suppression.Targeting DOT1L and HOX gene expression in MLL-rearranged leukemia and beyondAnimal models of acute myelogenous leukaemia - development, application and future perspectives.Modeling thyroid cancer in the mouse.Genetically engineered mouse models in cancer researchMouse chromosome engineering for modeling human disease.Cancer genetics of epigenetic genes.Non-parallel recombination limits Cre-LoxP-based reporters as precise indicators of conditional genetic manipulationReview: genetic models of acute myeloid leukaemia.Applications of the site-specific recombinase Cre to the study of genomic imprintingMolecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.Genetically engineered mouse models of human B-cell precursor leukemias.Somatic Engineering of Oncogenic Chromosomal Rearrangements: A PerspectiveMouse models of MLL leukemia: recapitulating the human diseaseDysregulation of haematopoietic stem cell regulatory programs in acute myeloid leukaemia.The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development.Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model.Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system.Creating a transloxation. Engineering interchromosomal translocations in the mouse.Generation of minipigs with targeted transgene insertion by recombinase-mediated cassette exchange (RMCE) and somatic cell nuclear transfer (SCNT).Mixed-Lineage Leukemia Fusions and Chromatin in Leukemia.Chromosomal translocation engineering to recapitulate primary events of human cancer.Chromosomal translocation master genes, mouse models and experimental therapeutics.The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice.Human MLL-AF9 Overexpression Induces Aberrant Hematopoietic Expansion in Zebrafish.The invertor knock-in conditional chromosomal translocation mimic
P2860
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P2860
Inter-chromosomal recombination of Mll and Af9 genes mediated by cre-loxP in mouse development.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@en
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@nl
type
label
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@en
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@nl
prefLabel
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@en
Inter-chromosomal recombinatio ...... cre-loxP in mouse development.
@nl
P2093
P2860
P356
P1433
P1476
Inter-chromosomal recombinatio ...... cre-loxP in mouse development
@en
P2093
P2860
P304
P356
10.1093/EMBO-REPORTS/KVD021
P577
2000-08-01T00:00:00Z