Familial hypertrophic cardiomyopathy related E180G mutation increases flexibility of human cardiac α-tropomyosin.
about
Energy landscapes reveal the myopathic effects of tropomyosin mutations.Tropomyosin de-phosphorylation in the heart: what are the consequences?N-acetylcysteine reverses diastolic dysfunction and hypertrophy in familial hypertrophic cardiomyopathy.Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137LSlowed Dynamics of Thin Filament Regulatory Units Reduces Ca(2+)-Sensitivity of Cardiac Biomechanical Function.Decreasing tropomyosin phosphorylation rescues tropomyosin-induced familial hypertrophic cardiomyopathyPredicting Effects of Tropomyosin Mutations on Cardiac Muscle Contraction through Myofilament Modeling.Nuclear tropomyosin and troponin in striated muscle: new roles in a new locale?Alpha-tropomyosin mutations in inherited cardiomyopathies.Maladaptive modifications in myofilament proteins and triggers in the progression to heart failure and sudden death.Pathogenesis associated with a restrictive cardiomyopathy mutant in cardiac troponin T is due to reduced protein stability and greatly increased myofilament Ca2+ sensitivity.The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.Investigating the effects of tropomyosin mutations on its flexibility and interactions with filamentous actin using molecular dynamics simulation.HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments.
P2860
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P2860
Familial hypertrophic cardiomyopathy related E180G mutation increases flexibility of human cardiac α-tropomyosin.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@en
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@nl
type
label
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@en
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@nl
prefLabel
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@en
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@nl
P2093
P2860
P1433
P1476
Familial hypertrophic cardiomy ...... f human cardiac α-tropomyosin.
@en
P2093
Campion K P Loong
Huan-Xiang Zhou
P Bryant Chase
P2860
P304
P356
10.1016/J.FEBSLET.2012.08.005
P407
P577
2012-08-14T00:00:00Z