Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.
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Kinases as druggable targets in trypanosomatid protozoan parasitesIdentification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaignEVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.Identification of "Preferred" Human Kinase Inhibitors for Sleeping Sickness Lead Discovery. Are Some Kinases Better than Others for Inhibitor Repurposing?Repurposing strategies for tropical disease drug discovery.In vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agentsOptimization of physicochemical properties for 4-anilinoquinazoline inhibitors of trypanosome proliferation.Novel lead compounds in pre-clinical development against African sleeping sickness
P2860
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P2860
Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Establishment of a structure-a ...... for African sleeping sickness.
@en
Establishment of a structure-a ...... for African sleeping sickness.
@nl
type
label
Establishment of a structure-a ...... for African sleeping sickness.
@en
Establishment of a structure-a ...... for African sleeping sickness.
@nl
prefLabel
Establishment of a structure-a ...... for African sleeping sickness.
@en
Establishment of a structure-a ...... for African sleeping sickness.
@nl
P2093
P2860
P50
P356
P1476
Establishment of a structure-a ...... for African sleeping sickness.
@en
P2093
Domingo I Rojas-Barros
João D Seixas
Manuela Berlanga
Pilar Manzano
Rosario Diaz
Sandra A Luengo-Arratta
Silvia Gonzalez
Terry K Smith
P2860
P304
P356
10.1021/JM500361R
P407
P577
2014-05-21T00:00:00Z