Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow.
about
Vascular inward rectifier K+ channels as external K+ sensors in the control of cerebral blood flowImprovement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemiaLocalized TRPA1 channel Ca2+ signals stimulated by reactive oxygen species promote cerebral artery dilationInversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels.Traumatic brain injury disrupts cerebrovascular tone through endothelial inducible nitric oxide synthase expression and nitric oxide gain of functionAKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.Intermediate-conductance calcium-activated potassium channels participate in neurovascular coupling.Immunosuppressive/anti-inflammatory cytokines directly and indirectly inhibit endothelial dysfunction--a novel mechanism for maintaining vascular functionFundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization.A critical role for the vascular endothelium in functional neurovascular coupling in the brain.Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery.Automated detection and measurement of isolated retinal arterioles by a combination of edge enhancement and cost analysisPotassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease.Plasma from patients with HELLP syndrome increases blood-brain barrier permeability.Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lungIntermediate conductance calcium-activated potassium channels modulate summation of parallel fiber input in cerebellar Purkinje cellsImpairment of IKCa channels contributes to uteroplacental endothelial dysfunction in rat diabetic pregnancy.Sympathetic nerve stimulation induces local endothelial Ca2+ signals to oppose vasoconstriction of mouse mesenteric arteries.Effect of hypertension and carotid occlusion on brain parenchymal arteriole structure and reactivityUnitary TRPV3 channel Ca2+ influx events elicit endothelium-dependent dilation of cerebral parenchymal arterioles.Recruitment of dynamic endothelial Ca2+ signals by the TRPA1 channel activator AITC in rat cerebral arteries.Ion channel networks in the control of cerebral blood flow.Ryanodine receptors, calcium signaling, and regulation of vascular tone in the cerebral parenchymal microcirculation.Role of impaired endothelial cell Ca(2+) signaling in uteroplacental vascular dysfunction during diabetic rat pregnancyReduced vascular smooth muscle BK channel current underlies heart failure-induced vasoconstriction in mice.Endothelial SK3 channel-associated Ca2+ microdomains modulate blood pressure.Astrocyte regulation of cerebral vascular tone.Mechanisms of enhanced basal tone of brain parenchymal arterioles during early postischemic reperfusion: role of ET-1-induced peroxynitrite generation.Neurovascular signaling in the brain and the pathological consequences of hypertension.K(Ca)2 and k(ca)3 channels in learning and memory processes, and neurodegeneration.T-type channels buddy up.Patch clamp.Hydrogen sulfide-induced vasodilation mediated by endothelial TRPV4 channels.Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channelsCapillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow.Endothelium-dependent hyperpolarization: out of the dish and into the brainPurinergic receptors regulate myogenic tone in cerebral parenchymal arterioles.Calcium and potassium channels in experimental subarachnoid hemorrhage and transient global ischemia.pCO(2) and pH regulation of cerebral blood flow.Acidosis dilates brain parenchymal arterioles by conversion of calcium waves to sparks to activate BK channels.
P2860
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P2860
Endothelial SK(Ca) and IK(Ca) channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Endothelial SK
@nl
Endothelial SK(Ca) and IK(Ca) ...... cortical cerebral blood flow.
@en
type
label
Endothelial SK
@nl
Endothelial SK(Ca) and IK(Ca) ...... cortical cerebral blood flow.
@en
prefLabel
Endothelial SK
@nl
Endothelial SK(Ca) and IK(Ca) ...... cortical cerebral blood flow.
@en
P2093
P2860
P356
P1476
Endothelial SK(Ca) and IK(Ca) ...... d cortical cerebral blood flow
@en
P2093
Adrian D Bonev
Kathryn M Dunn
Rachael M Hannah
P2860
P304
P356
10.1038/JCBFM.2010.214
P577
2010-12-22T00:00:00Z