about
Detecting somatic mutations in genomic sequences by means of Kolmogorov-Arnold analysisEnzyme redesign guided by cancer-derived IDH1 mutationsExome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas.2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations.Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolismCancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia.IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brainProfiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome.Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila.Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs.Relationship Between Time of First Publication and Subsequent Publication Success Among Non-PhD Physician-ScientistsTERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewalThe genome-wide mutational landscape of pituitary adenomas.Disruption of wild-type IDH1 suppresses D-2-hydroxyglutarate production in IDH1-mutated gliomas.IDH1 and IDH2 hotspot mutations are not found in canine glioma.Releasing the block: setting differentiation free with mutant IDH inhibitors.Promoting a new brain tumor mutation: TERT promoter mutations in CNS tumors.TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL.Smaller protein, larger therapeutic potential: PPM1D as a new therapeutic target in brainstem glioma.
P50
Q28608224-99D51124-C665-42C3-823B-5815AE16FB87Q28714280-D13C49EC-E69F-4743-994E-90FC368B0E41Q33813999-F4021AAC-FA38-4E2A-A950-11D5E0FBD142Q33822146-A554C04F-B071-4026-A3A3-43ACF8F5140FQ33965102-A1E67F6F-5ACD-4683-AC34-3D7FFE7B3C36Q34140953-4B59007D-3DCE-43A9-8F84-CB13F45210E0Q34330224-CCE7DB88-A8DD-407D-828B-183BBBC89ED1Q34602582-D36AC847-F52E-4A9F-8911-95E08DAEB757Q34876800-04BDA922-C032-4119-8158-5C557A34948FQ36013362-0ABDC5CF-C328-4C81-8E54-6E0D5D1CCC92Q36102706-3DBE0393-C78F-4052-9930-E6D8DA18E8D8Q36762656-6EA81DC4-02E7-4DF4-85C2-8A7A08906580Q37400088-95531278-A361-4B1F-AB4F-19C7E99C6C0EQ39233924-C30D6119-A9A8-4B8C-B9E3-CFDEDD2CAC3FQ41137508-1FFE1A8A-2BC0-49A2-B5DE-7405D95D49AEQ42498717-3A0A8ABA-DD02-4660-8EC9-752B6EABBAEFQ42746699-9C326834-2854-48E2-8475-31B28635D953Q46224386-1A54C82D-BC79-4761-9D01-B566F6FA50E5Q48451908-1A160FEC-D135-4CF6-AAF8-0E824ADE7DC8
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Zachary J Reitman
@ast
Zachary J Reitman
@en
Zachary J Reitman
@es
Zachary J Reitman
@nl
Zachary J Reitman
@sl
type
label
Zachary J Reitman
@ast
Zachary J Reitman
@en
Zachary J Reitman
@es
Zachary J Reitman
@nl
Zachary J Reitman
@sl
prefLabel
Zachary J Reitman
@ast
Zachary J Reitman
@en
Zachary J Reitman
@es
Zachary J Reitman
@nl
Zachary J Reitman
@sl
P106
P21
P31
P496
0000-0002-9122-9550
P569
2000-01-01T00:00:00Z