Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts. - Wikidata - awgldk - TriplyDB

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

http://www.wikidata.org/entity/Q42762796

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Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms Resorption-cycle-dependent polarization of mRNAs for different subunits of V-ATPase in bone-resorbing osteoclasts Targeted disruption of the Cl-/HCO3- exchanger Ae2 results in osteopetrosis in mice Hypoxic regulation of osteoclast differentiation and bone resorption activity The amino-terminal domain of the B subunit of vacuolar H+-ATPase contains a filamentous actin binding site Vacuolar and plasma membrane proton-adenosinetriphosphatases Immunocytochemical localization of cathepsins B and G in odontoclasts of human deciduous teeth V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs.Vacuolar-type H+-ATPase regulates cytoplasmic pH in Toxoplasma gondii tachyzoites.Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism.Current and potential future drug treatments for osteoporosis.ClC-7/Ostm1 contribute to the ability of tea polyphenols to maintain bone homeostasis in C57BL/6 mice, protecting against fluorosis Inhibition of osteoclast bone resorption by disrupting vacuolar H+-ATPase a3-B2 subunit interaction.Alternative splicing generates a second isoform of the catalytic A subunit of the vacuolar H(+)-ATPase.Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.Characterization of functional reprogramming during osteoclast development using quantitative proteomics and mRNA profiling.ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss.Odontoblast function seen as the response of dentinal tissue to dental caries.Intracellular membrane trafficking in bone resorbing osteoclasts.Proteomic study of different culture medium serum volume fractions on RANKL-dependent RAW264.7 cells differentiating into osteoclasts Extracellular fluid flow and chloride content modulate H(+) transport by osteoclasts.Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis Expression of 16 kDa proteolipid of vacuolar-type H(+)-ATPase in human pancreatic cancer.Monocytes/Macrophages Upregulate the Hyaluronidase HYAL1 and Adapt Its Subcellular Trafficking to Promote Extracellular Residency upon Differentiation into Osteoclasts.Rab13 is upregulated during osteoclast differentiation and associates with small vesicles revealing polarized distribution in resorbing cells.Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts Role of Na-H exchangers and vacuolar H+ pumps in intracellular pH regulation in neonatal rat osteoclasts.Tumor acidity, chemoresistance and proton pump inhibitors.Sensitivity to vanadate and isoforms of subunits A and B distinguish the osteoclast proton pump from other vacuolar H+ ATPases Reversal effects of pantoprazole on multidrug resistance in human gastric adenocarcinoma cells by down-regulating the V-ATPases/mTOR/HIF-1α/P-gp and MRP1 signaling pathway in vitro and in vivo.Recent trends in cancer drug resistance reversal strategies using nanoparticles.Roles of ion transport in control of cell motility.The cell biology and role of resorptive cells in diseases: A review.Osteopetrosis mutation R444L causes endoplasmic reticulum retention and misprocessing of vacuolar H+-ATPase a3 subunit.Effects of brefeldin-A: potent inhibitor of intracellular protein transport on ultrastructure and resorptive function of cultured osteoclasts.Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts.

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P2860

Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts.

http://www.wikidata.org/entity/Q42762796

description

1990 nî lūn-bûn

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1990年の論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年論文

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1990年论文

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1990年论文

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1990年论文

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name

Evidence for the presence of a proton pump of the vacuolar H

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Evidence for the presence of a ...... uffled borders of osteoclasts.

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type

label

Evidence for the presence of a proton pump of the vacuolar H

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Evidence for the presence of a ...... uffled borders of osteoclasts.

@en

prefLabel

Evidence for the presence of a proton pump of the vacuolar H

@nl

Evidence for the presence of a ...... uffled borders of osteoclasts.

@en

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Journal of Cell Biology

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Evidence for the presence of a ...... uffled borders of osteoclasts.

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Hentunen T

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Karhukorpi EK

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Lakkakorpi P

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Roininen I

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Sundquist K

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Tuukkanen J

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Wallmark B

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P2860

Protein measurement with the Folin phenol reagent

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Ultrastructural localization of intracellular antigens by the use of protein A-gold complex.

Osteoclastic bone resorption by a polarized vacuolar proton pump.

Structural studies of the vacuolar membrane ATPase from Neurospora crassa and comparison with the tonoplast membrane ATPase from Zea mays

Organization of osteoclast microfilaments during the attachment to bone surface in vitro.

The effects of parathyroid hormone, colchicine, and calcitonin on the ultrastructure and the activity of osteoclasts in organ culture.

Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border.

Structure, molecular genetics, and evolution of vacuolar H+-ATPases.

The sulphatase of ox liver. II. The purification and properties of sulphatase A.

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10.1083/JCB.111.3.1305

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3

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2144003

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