5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

Item
http://www.wikidata.org/entity/Q42771475
An overview on therapeutics attenuating amyloid β level in Alzheimer's disease: targeting neurotransmission, inflammation, oxidative stress and enhanced cholesterol levelsKey Targets for Multi-Target Ligands Designed to Combat NeurodegenerationRegulation of amyloid precursor protein processing by serotonin signalingAPP as a Protective Factor in Acute Neuronal Insults.Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.The serotonergic system and cognitive functionEarly administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.Modulating 5-HT4 and 5-HT6 receptors in Alzheimer's disease treatment.Stress-Induced Synaptic Dysfunction and Neurotransmitter Release in Alzheimer's Disease: Can Neurotransmitters and Neuromodulators be Potential Therapeutic Targets?Therapeutic Potential of Secreted Amyloid Precursor Protein APPsα.The Role of ADAM10 in Alzheimer's Disease.Developing BACE-1 inhibitors for FXS.Downregulation of ADAM10 expression inhibits metastasis and invasiveness of human hepatocellular carcinoma HepG2 cells.Non-amyloidogenic effects of α2 adrenergic agonists: implications for brimonidine-mediated neuroprotection.Serotoninergic antidepressants positively affect platelet ADAM10 expression in patients with Alzheimer's disease.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860

5-HT4 receptors constitutively promote the non-amyloidogenic pathway of APP cleavage and interact with ADAM10.

Item
http://www.wikidata.org/entity/Q42771475
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@en
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@nl
type
label
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@en
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@nl
prefLabel
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@en
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
5-HT4 receptors constitutively ...... vage and interact with ADAM10.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P932