about
The interferon-inducible IFI16 gene inhibits tube morphogenesis and proliferation of primary, but not HPV16 E6/E7-immortalized human endothelial cellsA direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs diseaseHippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures.Development of a New Tool for 3D Modeling for Regenerative MedicineMolecular analysis of behavior by gene transfer into neurons with herpes simplex vectors.Engineering herpes simplex virus vectors for CNS applications.Gene transfer into neurones for the molecular analysis of behaviour: focus on herpes simplex vectors.An attenuated herpes simplex virus type 1 (HSV1) encoding the HIV-1 Tat protein protects mice from a deadly mucosal HSV1 challengeThe HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses.Development and application of replication-incompetent HSV-1-based vectors.CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitisHSV as a vector in vaccine development and gene therapy.Characterization of herpes simplex virus 1 strains as platforms for the development of oncolytic viruses against liver cancer.Herpes simplex virus type 1-derived recombinant and amplicon vectors.Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo.Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo.Specific targeted binding of herpes simplex virus type 1 to hepatocytes via the human hepatitis B virus preS1 peptide.Fibroblast growth factor-II gene therapy reverts the clinical course and the pathological signs of chronic experimental autoimmune encephalomyelitis in C57BL/6 mice.Systemic immunodominant CD8 responses with an effector-like phenotype are induced by intravaginal immunization with attenuated HSV vectors expressing HIV Tat and mediate protection against HSV infection.Inhibition of human immunodeficiency virus reactivation from latency by a tat transdominant negative mutant.Herpes simplex virus type 1 (HSV-1)-derived amplicon vectors for gene transfer and gene therapy.Herpes simplex virus type 1 (HSV-1)-derived recombinant vectors for gene transfer and gene therapy.Erratum: CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis.MHC class I cross-presentation by dendritic cells counteracts viral immune evasion.Herpes simplex virus growth, preparation, and assay.Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus.Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectors.Progress in development of herpes simplex virus gene vectors for treatment of rheumatoid arthritis.Reduced immune responses after vaccination with a recombinant herpes simplex virus type 1 vector in the presence of antiviral immunity.HSV-1-mediated IL-1 receptor antagonist gene therapy ameliorates MOG(35-55)-induced experimental autoimmune encephalomyelitis in C57BL/6 mice.Transcriptional targeting of B cells for induction of peripheral CD8 T cell tolerance.Replication-deficient mutant Herpes Simplex Virus-1 targets professional antigen presenting cells and induces efficient CD4+ T helper responses.Expression of human immunodeficiency virus type 1 tat from a replication-deficient herpes simplex type 1 vector induces antigen-specific T cell responses.High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.Modulation of mucosal and systemic immunity by enteric administration of nonreplicating herpes simplex virus expressing cytokines.Cytokine therapy in immune-mediated demyelinating diseases of the central nervous system: a novel gene therapy approach.Connexin 43-enhanced suicide gene therapy using herpesviral vectors.Central nervous system gene therapy with interleukin-4 inhibits progression of ongoing relapsing-remitting autoimmune encephalomyelitis in Biozzi AB/H mice.Effects of defective herpes simplex vectors expressing neurotrophic factors on the proliferation and differentiation of nervous cells in vivo.Identification of replication-competent HSV-1 Cgal+ strain targets in a mouse model of human hepatocarcinoma xenograft.
P50
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P50
description
hulumtuese
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հետազոտող
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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P.C. Marconi
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P.C.R. Marconi
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Peggy C. Marconi
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Peggy C.R. Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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Peggy Marconi
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P106
P1153
7004929498
P21
P31
P496
0000-0003-3488-0491