Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin
about
Molecular Structure, Membrane Interactions, and Toxicity of the Islet Amyloid Polypeptide in Type 2 Diabetes MellitusZinc transporter 8 (ZnT8) and β cell functionThe Effects of Lipid Membranes, Crowding and Osmolytes on the Aggregation, and Fibrillation Propensity of Human IAPPOn the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP PeptidesMonoconjugation of Human Amylin with MethylpolyethyleneglycolConsidering protonation as a posttranslational modification regulating protein structure and function.Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding.Solution state structures of human pancreatic amylin and pramlintide.Defining the molecular basis of amyloid inhibitors: human islet amyloid polypeptide-insulin interactions.Biphasic effects of insulin on islet amyloid polypeptide membrane disruption.Preparation and characterization of PEGylated amylin.Mechanism of amylin fibrillization enhancement by heparin.Amyloid aggregation and deposition of human islet amyloid polypeptide at membrane interfaces.Small molecule screening in context: lipid-catalyzed amyloid formation.Misfolded proteins in Alzheimer's disease and type II diabetes.Structure-Based Small Molecule Modulation of a Pre-Amyloid State: Pharmacological Enhancement of IAPP Membrane-Binding and Toxicity.Membrane disruption and early events in the aggregation of the diabetes related peptide IAPP from a molecular perspectiveIslet Amyloid Polypeptide: Structure, Function, and Pathophysiology.Mechanism of Inhibition of Human Islet Amyloid Polypeptide-Induced Membrane Damage by a Small Organic Fluorogen.α-helix to β-hairpin transition of human amylin monomer.Ionic strength effects on amyloid formation by amylin are a complicated interplay among Debye screening, ion selectivity, and Hofmeister effectsEndosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicityFiber-dependent and -independent toxicity of islet amyloid polypeptide.The ability of insulin to inhibit the formation of amyloid by pro-islet amyloid polypeptide processing intermediates is significantly reduced in the presence of sulfated glycosaminoglycans.A peptidomimetic approach to targeting pre-amyloidogenic states in type II diabetesA two-site mechanism for the inhibition of IAPP amyloidogenesis by zinc.Role of zinc in human islet amyloid polypeptide aggregation.Inhibition of IAPP aggregation by insulin depends on the insulin oligomeric state regulated by zinc ion concentration.A direct fluorescence-based technique for cellular localization of amylin.Membrane-mediated amyloid deposition of human islet amyloid polypeptide.Assembly dynamics of two-beta sheets revealed by molecular dynamics simulations.Destabilization of Human Insulin Fibrils by Peptides of Fruit Bromelain Derived From Ananas comosus (Pineapple).
P2860
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P2860
Interaction of membrane-bound islet amyloid polypeptide with soluble and crystalline insulin
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Interaction of membrane-bound ...... oluble and crystalline insulin
@en
Interaction of membrane-bound ...... oluble and crystalline insulin
@nl
type
label
Interaction of membrane-bound ...... oluble and crystalline insulin
@en
Interaction of membrane-bound ...... oluble and crystalline insulin
@nl
prefLabel
Interaction of membrane-bound ...... oluble and crystalline insulin
@en
Interaction of membrane-bound ...... oluble and crystalline insulin
@nl
P2860
P356
P1433
P1476
Interaction of membrane-bound ...... oluble and crystalline insulin
@en
P2093
Andrew D Miranker
P2860
P304
P356
10.1110/PS.036350.108
P577
2008-09-02T00:00:00Z