about
The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesisThe beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cellsIdentification of stem cells in small intestine and colon by marker gene Lgr5Crypt stem cells as the cells-of-origin of intestinal cancerDiabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demandTranscription factor achaete scute-like 2 controls intestinal stem cell fateSOX9 is required for the differentiation of paneth cells in the intestinal epitheliumThe ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epitheliumWnt signalling induces maturation of Paneth cells in intestinal cryptsPaneth cells constitute the niche for Lgr5 stem cells in intestinal cryptsDe Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome DataLineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.Porcupine inhibitor suppresses paracrine Wnt-driven growth of Rnf43;Znrf3-mutant neoplasia.Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.Generation of an inducible colon-specific Cre enzyme mouse line for colon cancer research.Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters.Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition.Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomesAdenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
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P50
description
onderzoeker
@nl
name
Maaike van den Born
@ast
Maaike van den Born
@en
Maaike van den Born
@es
Maaike van den Born
@nl
Maaike van den Born
@sl
type
label
Maaike van den Born
@ast
Maaike van den Born
@en
Maaike van den Born
@es
Maaike van den Born
@nl
Maaike van den Born
@sl
prefLabel
Maaike van den Born
@ast
Maaike van den Born
@en
Maaike van den Born
@es
Maaike van den Born
@nl
Maaike van den Born
@sl
P106
P21
P31
P569
2000-01-01T00:00:00Z