ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
about
Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's diseaseClose and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiPUnfolded protein response-induced ERdj3 secretion links ER stress to extracellular proteostasis.Mutant glucocerebrosidase in Gaucher disease recruits Hsp27 to the Hsp90 chaperone complex for proteasomal degradationLysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.Erdj3 Has an Essential Role for Z Variant Alpha-1-Antitrypsin Degradation.Mapping and Exploring the Collagen-I Proteostasis Network.How Do J-Proteins Get Hsp70 to Do So Many Different Things?New Directions in Gaucher Disease.Mapping wild-type and R345W fibulin-3 intracellular interactomes.Stabilization of Glucocerebrosidase by Active Site Occupancy.Regulating extracellular proteostasis capacity through the unfolded protein response.Neurons Export Extracellular Vesicles Enriched in Cysteine String Protein and Misfolded Protein Cargo.Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s.Adapting Secretory Proteostasis and Function Through the Unfolded Protein Response.Dysregulation of the autophagic-lysosomal pathway in Gaucher and Parkinson's disease.
P2860
Q28074143-9B0BA2AD-FB0A-4F71-820E-439B96145CD2Q28270851-5F5975C7-38CF-4323-8137-119A7C620050Q34923990-4237F981-BA51-4BAF-AC26-C6264AD4037FQ35037986-4FF3627F-A9C8-4857-9E5F-BBA772CCCB49Q35858682-9E5B421E-0B25-4DA9-B840-6536B3B17250Q38698836-88E953F7-D08B-4EB2-95F8-C274839BBA68Q38707103-56AFAF35-A46D-45FD-B051-75EC2700372DQ38796333-1CA25A9D-5DFD-4EC3-9935-CDC98AF23A7BQ38897201-44CDB773-065F-48CE-9813-330246FE0E70Q38905996-6293E64E-4394-495B-9BD3-800413C1CB9DQ38989803-5C1F1B60-CEAD-4CCA-97CD-39511B4E2D31Q41110570-EC2319A6-9E2D-4388-A058-30E124F1AA90Q41887040-C0F9E972-05F3-4D21-9470-8CA560C4A8D6Q42269174-3C350D33-88BE-4C81-9161-4A083CC55813Q44710284-8BA24646-9138-4B43-A3AD-6CA6D8AD0779Q47774233-50A30DDD-B64C-4022-96BE-11EBF0378D6EQ52689754-66519183-9F1B-4453-AD4A-E8CD8EBA28A9
P2860
ERdj3 is an endoplasmic reticulum degradation factor for mutant glucocerebrosidase variants linked to Gaucher's disease.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@en
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@nl
type
label
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@en
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@nl
prefLabel
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@en
ERdj3 is an endoplasmic reticu ...... s linked to Gaucher's disease.
@nl
P2093
P2860
P1476
ERdj3 is an endoplasmic reticu ...... ts linked to Gaucher's disease
@en
P2093
John R Yates
Joseph C Genereux
Sandra Pankow
Yun Lei Tan
P2860
P304
P356
10.1016/J.CHEMBIOL.2014.06.008
P577
2014-08-01T00:00:00Z