NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis. - Wikidata - awgldk - TriplyDB

NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis.

NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis.

http://www.wikidata.org/entity/Q42809972

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Synbindin, A novel syndecan-2-binding protein in neuronal dendritic spines SHP-2 mediates target-regulated axonal termination and NGF-dependent neurite growth in sympathetic neurons Delineating neurotrophin-3 dependent signaling pathways underlying sympathetic axon growth along intermediate targets.Differential regulation of trkA and p75 in noradrenergic pelvic autonomic ganglion cells after deafferentation of their cholinergic neighbours.Phosphoinositide 3-kinase regulates crosstalk between Trk A tyrosine kinase and p75(NTR)-dependent sphingolipid signaling pathways.NGF-promoted axon growth and target innervation requires GITRL-GITR signaling.Peripheral nerve regeneration and neurotrophic factors.VEGF-A and Semaphorin3A: modulators of vascular sympathetic innervation.Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease.The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death Activity-dependent activation of TrkB neurotrophin receptors in the adult CNS.Regulation of neuronal survival and death by extracellular signals during development.Neurotrophin-3 promotes the cholinergic differentiation of sympathetic neurons.The brown fat secretome: metabolic functions beyond thermogenesis.Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures.SIV infection decreases sympathetic innervation of primate lymph nodes: the role of neurotrophins Regulation of cardiac innervation and function via the p75 neurotrophin receptor.Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit.Abnormal sympathetic nervous system development and physiological dysautonomia in Egr3-deficient mice.APPL1: role in adiponectin signaling and beyond Sympathetic denervation of peri-infarct myocardium requires the p75 neurotrophin receptor.Microarray analyses of pituitary adenylate cyclase activating polypeptide (PACAP)-regulated gene targets in sympathetic neurons.Wnt5a mediates nerve growth factor-dependent axonal branching and growth in developing sympathetic neurons.Peripheral nerve injury modulates neurotrophin signaling in the peripheral and central nervous system.Characterization of canine dental pulp cells and their neuroregenerative potential.Retrograde transport of neurotrophic factor signaling: implications in neuronal development and pathogenesis.Neurotrophin signaling endosomes: biogenesis, regulation, and functions.Establishment of a cellular model to study TrkC-dependent neuritogenesis.APPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction.Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF.A multipotent clonal human periodontal ligament cell line with neural crest cell phenotypes promotes neurocytic differentiation, migration, and survival.TrkA receptor "hot spots" for binding of NT-3 as a heterologous ligand.TrkA induces apoptosis of neuroblastoma cells and does so via a p53-dependent mechanism.Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival.Mitogen-activated protein kinase inhibition reveals differences in signalling pathways activated by neurotrophin-3 and other growth-stimulating conditions of adult mouse dorsal root ganglia neurons.TrkA amino acids controlling specificity for nerve growth factor.p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors.SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase Gangliosides activate Trk receptors by inducing the release of neurotrophins.Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival.

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NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis.

http://www.wikidata.org/entity/Q42809972

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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type

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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NGF and neurotrophin-3 both ac ...... e survival and neuritogenesis.

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Belliveau DJ

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Kaplan D

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Kohn J

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Krivko I

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Lachance C

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Miller FD

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Pozniak C

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P2860

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

trkC encodes multiple neurotrophin-3 receptors with distinct biological properties and substrate specificities

Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons

Isotypes of alpha-tubulin are differentially regulated during neuronal maturation

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in Xenopus ovary

Binding of neurotrophin-3 to p75LNGFR, TrkA, and TrkB mediated by a single functional epitope distinct from that recognized by trkC

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

The neurotrophic factors brain-derived neurotrophic factor and neurotrophin-3 are ligands for the trkB tyrosine kinase receptor

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

Alternative forms of rat TrkC with different functional capabilities

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375-388

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2

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136

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Dmitri A. Rusakov

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9015308

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2134821

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