The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.
about
A PCR-mutagenesis strategy for rapid detection of mutations in codon 634 of the ret proto-oncogene related to MEN 2A.Ligand-independent dimerization and activation of the oncogenic Xmrk receptor by two mutations in the extracellular domain.The sensitivity of activated Cys Ret mutants to glial cell line-derived neurotrophic factor is mandatory to rescue neuroectodermic cells from apoptosis.Melanoma development and pigment cell transformation in xiphophorus.Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions.Genetic alterations in medullary thyroid cancer: diagnostic and prognostic markers.A novel type of mutation in the cysteine rich domain of the RET receptor causes ligand independent activation.New insights in the molecular signature of advanced medullary thyroid cancer: evidence of a bad outcome of cases with double RET mutations.Genetic and Epigenetic of Medullary Thyroid Cancer.
P2860
Q24794563-DEC3392C-8561-4754-8FB0-7D936FC2AC82Q31473336-D7A57BF7-F576-492C-A01B-AC883A6A9357Q34012396-D585386B-A303-4397-95B8-1BDCFB1C5235Q34872771-2CD6BE3E-DEB7-4C86-A450-9FFA7ABFA13BQ37009001-B80D6AEA-A860-4519-B3B5-BB3406A45662Q38956444-C60BA7DC-72C0-4877-BCF4-A6908AC146D5Q40820055-787E7355-CC35-4C3C-AE3B-B045BF916C0AQ42798990-AF5EC282-7F2E-4B80-A056-7D8B0FB41D06Q52984965-C0829F7A-BB56-4450-B027-E77416D3032EQ55008552-4025F574-9ECF-45DE-8519-B3F2DFF18296
P2860
The Glu632-Leu633 deletion in cysteine rich domain of Ret induces constitutive dimerization and alters the processing of the receptor protein.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@en
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@nl
type
label
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@en
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@nl
prefLabel
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@en
The Glu632-Leu633 deletion in ...... ssing of the receptor protein.
@nl
P2093
P2860
P356
P1433
P1476
The Glu632-Leu633 deletion in ...... essing of the receptor protein
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202848
P407
P577
1999-08-01T00:00:00Z
P5875
P6179
1022495185