Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
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Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6Phospholipase D2 Enhances Epidermal Growth Factor-Induced Akt Activation in EL4 Lymphoma Cells.Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerThe exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).Phospholipase D: enzymology, functionality, and chemical modulationPEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase DTargeting mTOR-mediated survival signals in anticancer therapeutic strategies.Mutation of Y179 on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K-and Akt-dependent manner.Phospholipase D elevates the level of MDM2 and suppresses DNA damage-induced increases in p53.Phosphatidic acid signaling to mTOR: signals for the survival of human cancer cells.Targeting phospholipase D with small-molecule inhibitors as a potential therapeutic approach for cancer metastasis.Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C.Inhibition of platelet-derived growth factor-induced cell growth signaling by a short interfering RNA for EWS-Fli1 via down-regulation of phospholipase D2 in Ewing sarcoma cells.Alternative phospholipase D/mTOR survival signal in human breast cancer cells.Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells.Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cellsPhospholipase D and Its Essential Role in Cancer.Elevated phospholipase D activity in androgen-insensitive prostate cancer cells promotes both survival and metastatic phenotypes.MARCKS and MARCKS-like proteins in development and regeneration.
P2860
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P2860
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@en
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@nl
type
label
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@en
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@nl
prefLabel
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@en
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@nl
P2093
P2860
P356
P1433
P1476
Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.
@en
P2093
Annika Bryant
David A Foster
Eugen Kerkhoff
Paul Frankel
Roger Wooden
Troy Joseph
Ulf R Rapp
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205380
P407
P577
2002-05-01T00:00:00Z
P5875
P6179
1016482953