about
Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cellsPhosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptorS6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2Role of lipotoxicity in endothelial dysfunctionNew insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallateAspirin inhibits serine phosphorylation of insulin receptor substrate 1 in tumor necrosis factor-treated cells through targeting multiple serine kinasesPKC-zeta mediates insulin effects on glucose transport in cultured preadipocyte-derived human adipocytesExtracellular conversion of adiponectin hexamers into trimersPhosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to inProtein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin.Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps.Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: roles for AMP-activated protein kinase, Akt, and FOXO1Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complicationsG(s)alpha deficiency in adipose tissue leads to a lean phenotype with divergent effects on cold tolerance and diet-induced thermogenesisQuantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans.SirT1 enhances survival of human osteoarthritic chondrocytes by repressing protein tyrosine phosphatase 1B and activating the insulin-like growth factor receptor pathway.Simvastatin improves flow-mediated dilation but reduces adiponectin levels and insulin sensitivity in hypercholesterolemic patientsModulation of adiponectin as a potential therapeutic strategy.FOXO1 represses peroxisome proliferator-activated receptor-gamma1 and -gamma2 gene promoters in primary adipocytes. A novel paradigm to increase insulin sensitivity.Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance or endothelial dysfunction in lean or obese subjects.Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA.Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage.Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome.Insulin and the insulin receptor in experimental models of learning and memory.Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators.Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms.Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling.Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction.Adiponectin and cardiovascular disease: response to therapeutic interventions.Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance.Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulinInsulin action and insulin resistance in vascular endothelium.Vascular and metabolic effects of treatment of combined hyperlipidemia: focus on statins and fibrates.Are statins effective for simultaneously treating dyslipidemias and hypertension?Leptin and cardiovascular disease: response to therapeutic interventionsInsulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}C-reactive protein inhibits insulin activation of endothelial nitric oxide synthase via the immunoreceptor tyrosine-based inhibition motif of FcgammaRIIB and SHIP-1.Differential metabolic effects of pravastatin and simvastatin in hypercholesterolemic patients.Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats.Exenatide treatment for 6 months improves insulin sensitivity in adults with type 1 diabetes.
P50
Q24291346-7006696D-CF22-4E97-B0E7-E2AEB23FA562Q24291742-DA1959E1-F781-4D0D-8DC4-48AE5FD328B6Q24309036-C97EA06C-1E4F-4300-8D8E-6A3ED8360751Q27000731-B4EAD478-BFDF-4AA0-8B79-19D225416C43Q27012831-2AE4A75A-A2E3-4FBC-803B-C240B3A44195Q28195772-03420976-4CA6-4617-ABCD-F4CB03D7B8F9Q28218162-A9CAAEDB-F538-4A5C-8F83-915370DE51DCQ28579100-20DCD35C-5F4B-4FD4-A9E5-DE71F514AFB7Q31162696-7DACA112-80AB-4F36-8DA5-DCB99580ED4DQ31527752-038E32C6-8AA2-4293-A221-DCB5E6B86048Q33516103-53A6E51A-420B-4B83-B827-CC8AE6D4C8BEQ33577496-DA42D775-BDB0-461F-BEE8-5D029D91B18BQ33816859-B39B1E9E-3A40-4793-BF27-F30168941B56Q33824683-D83B78F2-8B39-4954-9EDC-47F5533CDDDFQ33910338-204DB678-8D35-4EE4-AC13-3E3737EA0C36Q34072652-EAB2E52B-0885-4081-B070-29EC14549FB2Q34177113-CBDDD34A-B7C7-460B-8892-5E050DD4F521Q34408711-E7E11EB7-432C-4697-941B-83851EC14E40Q34521158-F050AA34-ED9B-4540-A410-E56485E59A04Q34576668-2A2A2C9F-CA72-49F0-8B9D-C4DA16EA93FDQ34675892-96CF7BF9-5A29-4868-9447-C5F537069347Q34706104-FE1107E1-1D96-4978-BBA5-667C6C596D2BQ34894220-FF9445D0-1A87-4D66-8301-9DDAC6192752Q35749624-A761746E-5647-4C7C-8E31-D13F90ADBB7CQ36288762-2B806463-F0EE-4A4F-8F9E-E3B5C69B7E53Q36450952-FBDCD723-5CFD-4382-9E91-4B96B3D1212DQ36578889-4BFF6B5E-88E4-4643-A95B-37409270BF35Q36706086-90949153-C02F-455D-8D24-0546C38EE9D0Q36727352-EBD03624-5D79-4CD5-BDE1-839E6073508CQ36807686-F7E2A420-4F6A-44D4-A745-AD546FEC8627Q36836199-B22EB797-2A02-41EE-BE86-9E7B0E06F384Q36847470-5A0BD4EF-2EF3-402D-A014-596A70F71C88Q36894180-B3A33B50-E33B-4BF9-89B2-E184B21C67AAQ36896062-7A57B563-98D8-4110-B221-5BB206B4AA34Q37198354-AF4E9EAB-EB47-47BD-B9F7-81A7F4D481CCQ37253971-FE9DC813-04AC-4470-8C87-CE44D1331669Q37323477-EE72AF72-827A-4E5A-B7E9-067909E9B2A3Q37362218-7C5CB2BB-DC01-4E42-9BDC-FE9BBBF4E925Q37430821-36366B46-0197-4D16-8848-0820351FA442Q37597010-F15EEECE-5089-426F-8C31-156452355F6A
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Michael J. Quon
@ast
Michael J. Quon
@en
Michael J. Quon
@es
Michael J. Quon
@nl
Michael J. Quon
@sl
type
label
Michael J. Quon
@ast
Michael J. Quon
@en
Michael J. Quon
@es
Michael J. Quon
@nl
Michael J. Quon
@sl
prefLabel
Michael J. Quon
@ast
Michael J. Quon
@en
Michael J. Quon
@es
Michael J. Quon
@nl
Michael J. Quon
@sl
P106
P1153
7007172848
P21
P31
P496
0000-0002-9601-9915