Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts.
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Runx2 controls a feed-forward loop between androgen and prolactin-induced protein (PIP) in stimulating T47D cell proliferationMuMoD: a Bayesian approach to detect multiple modes of protein-DNA binding from genome-wide ChIP dataRUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.Genetic deletion of Nrf2 promotes immortalization and decreases life span of murine embryonic fibroblasts.The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motilityFrequent infection of human cancer xenografts with murine endogenous retroviruses in vivo.Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.The RUNX Genes as Conditional Oncogenes: Insights from Retroviral Targeting and Mouse Models.The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell linesThe osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts.Oncogene-induced senescence: an essential role for Runx.RUNX3 is multifunctional in carcinogenesis of multiple solid tumors.RUNX2 in mammary gland development and breast cancer.Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival.The RUNX family: developmental regulators in cancer.Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis.Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis.Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress.Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis.Runx regulation of sphingolipid metabolism and survival signaling.RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins.Roles of RUNX in Solid Tumors.
P2860
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P2860
Runx2 disruption promotes immortalization and confers resistance to oncogene-induced senescence in primary murine fibroblasts.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@en
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@nl
type
label
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@en
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@nl
prefLabel
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@en
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@nl
P2093
P2860
P1433
P1476
Runx2 disruption promotes immo ...... in primary murine fibroblasts.
@en
P2093
Alma Jenkins
Anna Kilbey
Anne Terry
Ewan R Cameron
James C Neil
Linda Hanlon
Margaret Bell
Sandy Wotton
P2860
P304
11263-11271
P356
10.1158/0008-5472.CAN-07-3016
P407
P50
P577
2007-12-01T00:00:00Z