Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.
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The role of Src in solid tumorsNovel advances in pancreatic cancer treatmentDown-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cellsPhosphorylation of the SRC epithelial substrate Trask is tightly regulated in normal epithelia but widespread in many human epithelial cancers.Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cellsCombined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growthOncogenic Ras/Src cooperativity in pancreatic neoplasia.Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.Improved angiostatic activity of dasatinib by modulation with hydrophobic chainsProcess of hepatic metastasis from pancreatic cancer: biology with clinical significance.Dasatinib enhances antitumor activity of paclitaxel in ovarian cancer through Src signaling.Mechanisms regulating colorectal cancer cell metastasis into liver (Review).Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis.Src protein tyrosine kinase family and acute inflammatory responses.Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair.Small molecule signal transduction inhibitors for the treatment of solid tumors.Integrating biologically targeted therapy in head and neck squamous cell carcinomasDasatinib inhibits the growth of prostate cancer in bone and provides additional protection from osteolysis.New treatment options for advanced pancreatic cancer.Srcasm inhibits Fyn-induced cutaneous carcinogenesis with modulation of Notch1 and p53.Molecular changes in pancreatic cancer.Dasatinib in solid tumors.A guide to picking the most selective kinase inhibitor tool compounds for pharmacological validation of drug targets.Pharmacology of Src family kinases and therapeutic implications of their modulators.Impact of the SRC inhibitor dasatinib on the metastatic phenotype of human prostate cancer cells.Inhibition of cell growth and up-regulation of MAD2 in human oesophageal squamous cell carcinoma after treatment with the Src/Abl inhibitor dasatinib.Loss of tyrosine phosphatase-dependent inhibition promotes activation of tyrosine kinase c-Src in detached pancreatic cells.Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling.Combined inhibition of c-Src and epidermal growth factor receptor abrogates growth and invasion of head and neck squamous cell carcinomaMechanism for Src activation by the CCK2 receptor: Patho-physiological functions of this receptor in pancreas.Differing Src signaling levels have distinct outcomes in Drosophila.Vascular targeting in pancreatic cancer: the novel tubulin-binding agent ZD6126 reveals antitumor activity in primary and metastatic tumor models.Src inhibition is still a relevant target in pancreatic cancerSmooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.Dual Src and EGFR inhibition in combination with gemcitabine in advanced pancreatic cancer: phase I results : A phase I clinical trial.Src kinase phosphorylates Notch1 to inhibit MAML bindingDown-regulation of cathepsin S and matrix metalloproteinase-9 via Src, a non-receptor tyrosine kinase, suppresses triple-negative breast cancer growth and metastasis
P2860
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P2860
Inhibition of SRC tyrosine kinase as treatment for human pancreatic cancer growing orthotopically in nude mice.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@en
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@nl
type
label
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@en
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@nl
prefLabel
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@en
Inhibition of SRC tyrosine kin ...... g orthotopically in nude mice.
@nl
P2093
P1476
Inhibition of SRC tyrosine kin ...... ng orthotopically in nude mice
@en
P2093
Alan Barge
Christiane J Bruns
Gudrun Koehl
Karl-Walter Jauch
Maksim V Yezhelyev
Markus Guba
Michael Fennell
Thomas Brabletz
P304
P356
10.1158/1078-0432.CCR-04-0621
P407
P577
2004-12-01T00:00:00Z