Kinetic mechanism and characterization of human beta-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells
about
Impaired elastic-fiber assembly by fibroblasts from patients with either Morquio B disease or infantile GM1-gangliosidosis is linked to deficiency in the 67-kD spliced variant of beta-galactosidase.Crystal Structure of Human -Galactosidase: STRUCTURAL BASIS OF GM1 GANGLIOSIDOSIS AND MORQUIO B DISEASESGamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of actionThe 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding proteinTowards a human repertoire of monocytic lysosomal proteins.Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly.Molecular consequences of the pathogenic mutation in feline GM1 gangliosidosisIdentification of Glu-268 as the catalytic nucleophile of human lysosomal beta-galactosidase precursor by mass spectrometry.Low p16INK4a Expression in Early Passage Human Prostate Basal Epithelial Cells Enables Immortalization by Telomerase Expression Alone.Maturation and degradation of beta-galactosidase in the post-Golgi compartment are regulated by cathepsin B and a non-cysteine protease.Insights into post-translational processing of beta-galactosidase in an animal model resembling late infantile human G-gangliosidosis.Early proteolytic cleavage with loss of a C-terminal fragment underlies altered processing of the beta-galactosidase precursor in galactosialidosisCharacterization of beta-galactosidase mutations Asp332-->Asn and Arg148-->Ser, and a polymorphism, Ser532-->Gly, in a case of GM1 gangliosidosisThioglycoligase-based assembly of thiodisaccharides: screening as beta-galactosidase inhibitorsGeneration and characterization of recombinant feline beta-galactosidase for preclinical enzyme replacement therapy studies in GM1 gangliosidosis.Polyethylene glycol-b-poly(lactic acid) polymersomes as vehicles for enzyme replacement therapy.GM1 gangliosidosis and Morquio B disease: expression analysis of missense mutations affecting the catalytic site of acid beta-galactosidase.
P2860
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P2860
Kinetic mechanism and characterization of human beta-galactosidase precursor secreted by permanently transfected Chinese hamster ovary cells
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@en
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@nl
type
label
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@en
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@nl
prefLabel
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@en
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@nl
P2093
P2860
P356
P1433
P1476
Kinetic mechanism and characte ...... ed Chinese hamster ovary cells
@en
P2093
Callahan JW
McCarter JD
Okamura-Oho Y
Withers SG
P2860
P304
P356
10.1042/BJ3040281
P407
P478
304 ( Pt 1)
P577
1994-11-01T00:00:00Z