Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin.
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Characterization of glucokinase-binding protein epitopes by a phage-displayed peptide library. Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel interaction partnerAntidiabetic effects of glucokinase regulatory protein small-molecule disruptorsFatty acid and amino acid modulation of glucose cycling in isolated rat hepatocytesContributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the elevated glycolysis in hepatocytes from Zucker fa/fa ratsGlucose induces the translocation of glycogen synthase to the cell cortex in rat hepatocytesDefect in glucokinase translocation in Zucker diabetic fatty ratsIntracellular distribution of hepatic glucokinase and glucokinase regulatory protein during the fasted to refed transition in ratsIdentification of fructose 6-phosphate- and fructose 1-phosphate-binding residues in the regulatory protein of glucokinaseCo-localization of glucokinase with actin filamentsNuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinaseEffect of streptozotocin-induced diabetes on glycogen resynthesis in fasted rats post-high-intensity exercise.Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.Controversies about sugars: results from systematic reviews and meta-analyses on obesity, cardiometabolic disease and diabetesBiophysical characterization of the interaction between hepatic glucokinase and its regulatory protein: impact of physiological and pharmacological effectors.Inhibition of glucokinase translocation by AMP-activated protein kinase is associated with phosphorylation of both GKRP and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.Discovery of Small-Molecule Glucokinase Regulatory Protein Modulators That Restore Glucokinase Activity.A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulinLiver glucokinase: An overview on the regulatory mechanisms of its activity.Glucagon induces translocation of glucokinase from the cytoplasm to the nucleus of hepatocytes by transfer between 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase-2 and the glucokinase regulatory protein.An unusual high-Km hexokinase is expressed in the mhAT3F hepatoma cell line.Intracellular pH governs the subcellular distribution of hexokinase in a glioma cell lineShared control of hepatic glycogen synthesis by glycogen synthase and glucokinase.The regulatory protein of glucokinase binds to the hepatocyte matrix, but, unlike glucokinase, does not translocate during substrate stimulationTime-dependent mechanisms in beta-cell glucose sensing.Glucokinase and glucokinase regulatory protein: mutual dependence for nuclear localization.Hepatic intralobular mapping of fructose metabolism in the rat liver.Investigation on the mechanism by which fructose, hexitols and other compounds regulate the translocation of glucokinase in rat hepatocytes.Glucokinase thermolability and hepatic regulatory protein binding are essential factors for predicting the blood glucose phenotype of missense mutations.Investigation of the mechanism by which glucose analogues cause translocation of glucokinase in hepatocytes: evidence for two glucose binding sites.Diets enriched in sucrose or fat increase gluconeogenesis and G-6-Pase but not basal glucose production in rats.Overexpression of protein targeting to glycogen (PTG) in rat hepatocytes causes profound activation of glycogen synthesis independent of normal hormone- and substrate-mediated regulatory mechanisms.Hexokinase and glucokinase binding in permeabilized guinea-pig hepatocytesSubstrate modulation of aldolase B binding in hepatocytes.Involvement of glucokinase translocation in the mechanism by which resorcinol inhibits glycolysis in hepatocytes.Long-term maintenance of low concentrations of fructose for the study of hepatic glucose phosphorylation.Use of alpha-toxin from Staphylococcus aureus to test for channelling of intermediates of glycolysis between glucokinase and aldolase in hepatocytes.Evolution of vertebrate glucokinase regulatory protein from a bacterial N-acetylmuramate 6-phosphate etherase.Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysis of glucose 1-phosphate.Effects of free fatty acids on hepatic glycogenolysis and gluconeogenesis in conscious dogs.A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin.
P2860
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P2860
Intracellular binding of glucokinase in hepatocytes and translocation by glucose, fructose and insulin.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Intracellular binding of gluco ...... glucose, fructose and insulin.
@en
Intracellular binding of gluco ...... glucose, fructose and insulin.
@nl
type
label
Intracellular binding of gluco ...... glucose, fructose and insulin.
@en
Intracellular binding of gluco ...... glucose, fructose and insulin.
@nl
prefLabel
Intracellular binding of gluco ...... glucose, fructose and insulin.
@en
Intracellular binding of gluco ...... glucose, fructose and insulin.
@nl
P2860
P356
P1433
P1476
Intracellular binding of gluco ...... glucose, fructose and insulin.
@en
P2860
P304
P356
10.1042/BJ2960785
P407
P478
296 ( Pt 3)
P577
1993-12-01T00:00:00Z