Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin.
about
p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.Leupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading.Gbeta gamma-independent coupling of alpha2-adrenergic receptor to p21(rhoA) in preadipocytesJanus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transductionTyrosine phosphorylation of paxillin and focal adhesion kinase by activation of muscarinic m3 receptors is dependent on integrin engagement by the extracellular matrixThe RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organizationInteraction of focal adhesion kinase with cytoskeletal protein talinTyrosine phosphorylation of p130(cas) by bombesin, lysophosphatidic acid, phorbol esters, and platelet-derived growth factor. Signaling pathways and formation of a p130(cas)-Crk complexFocal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protectionEpidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeletonActivation of the osmo-sensitive chloride conductance involves P21rho and is accompanied by a transient reorganization of the F-actin cytoskeleton.The effects of the small GTPase RhoA on the muscarinic contraction of airway smooth muscle result from its role in regulating actin polymerization.Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAKManipulating actin dynamics affects human in vitro decidualization.Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis.Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progressionIntegrin-mediated signals regulated by members of the rho family of GTPases.Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading.ECM-stimulated signaling and actin reorganization in embryonic corneal epithelia are Rho dependentBombesin-induced gastrin release from canine G cells is stimulated by Ca2+ but not by protein kinase C, and is enhanced by disruption of rho/cytoskeletal pathways.Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases.Neuropeptide-stimulated cell migration in prostate cancer cells is mediated by RhoA kinase signaling and inhibited by neutral endopeptidase.Galpha12 and Galpha13 stimulate Rho-dependent tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130 Crk-associated substrate.Leukotriene D4-induced mobilization of intracellular Ca2+ in epithelial cells is critically dependent on activation of the small GTP-binding protein Rho.Lysophosphatidic acid-induced activation of protein Ser/Thr kinases in cultured rat 3Y1 fibroblasts. Possible involvement in rho p21-mediated signalling.Galpha(13) stimulates Rho-dependent activation of the cyclooxygenase-2 promoter.Tyrosine phosphorylation of p125(Fak), p130(Cas), and paxillin does not require extracellular signal-regulated kinase activation in Swiss 3T3 cells stimulated by bombesin or platelet-derived growth factor.[D-Arg(1),D-Trp(5,7,9),Leu(11)]Substance P inhibits bombesin-induced mitogenic signal transduction mediated by both G(q) and G(12) in Swiss 3T3cells.ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts.Guanosine 5'-3-O-(thio)triphosphate stimulates tyrosine phosphorylation of p125FAK and paxillin in permeabilized Swiss 3T3 cells. Role of p21rho.Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cells.[D-Arg1,D-Trp5,7,9,Leu11]Substance P coordinately and reversibly inhibits bombesin- and vasopressin-induced signal transduction pathways in Swiss 3T3 cells.Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase.Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases.Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells.Sphingosylphosphorylcholine rapidly induces tyrosine phosphorylation of p125FAK and paxillin, rearrangement of the actin cytoskeleton and focal contact assembly. Requirement of p21rho in the signaling pathway.Identification of Glu173 as the critical amino acid residue for the ADP-ribosyltransferase activity of Clostridium botulinum C3 exoenzyme.Protein kinase D potentiates DNA synthesis and cell proliferation induced by bombesin, vasopressin, or phorbol esters in Swiss 3T3 cells.Bombesin, vasopressin, lysophosphatidic acid, and sphingosylphosphorylcholine induce focal adhesion kinase activation in intact Swiss 3T3 cells.
P2860
Q24316148-9562EA40-031E-495B-96E4-17590CA0E31EQ24319896-10266662-1D33-4AA4-A4C1-9746DF16CF40Q24324765-4F6BED52-CE81-4887-B828-79C0B22237F5Q24654170-C6EDBBD2-667C-47E7-A96F-93D4AA432469Q28118175-58493C3A-E0A8-4442-8C35-616945CFD200Q28200945-AED3512E-3C1B-4630-984C-DAE63DE1728DQ28294149-3992409E-76EC-4D34-B200-90698D0F07C2Q28507631-15AC25EF-2C43-4456-91DB-D3582CFCB0EFQ28571389-6B481F16-E5EC-460D-B548-69BF06404AC9Q28581924-25803C92-AA0C-4BC6-8206-965957BCDB31Q30450977-23894C3D-4A5D-4B84-80A1-08C860C58F08Q34085628-21AAAA1F-9D16-454D-A871-72B5FAE50D5AQ34467657-11439623-8090-47FA-87A1-A17A70D5EAB4Q34756529-B90207E4-06CA-46A3-9622-568E630C9794Q34979452-AEAE868C-8A0E-464F-A824-63538FB5A125Q35621434-37B0A7AE-6CF8-45D1-B01D-C65364A2AE98Q36255528-9B044E8C-B051-48A8-8CD7-783272273448Q36256316-F53585FD-65A7-49CB-BF9B-BA02420175EFQ36901472-DEC7635F-169A-49F8-A707-77F5BA1A03FCQ37350008-63ED5DB7-5FD9-4BCA-BC13-97BA7A827376Q37371588-BE44617E-EB9D-4CE2-A6FF-34E9A624F75BQ38337972-C5C26712-EC86-436E-AE1E-E4BD7433733EQ40284709-9ACF0B08-5566-4F80-B2BD-E95A042AAD32Q41035564-F49A234D-FFFE-4771-9101-FFB523D42373Q41198596-7138F33C-111E-44D2-9A4B-4EF66E11AB49Q41336296-77BEF970-E55A-409D-8E2B-B5C1BF18BD43Q41690566-AB918B48-781B-49DD-B319-750DAC4B84AEQ41727098-308C6633-AE65-49F9-AF54-31046A9BF8D4Q41745121-D6DB08A1-A98F-428C-BF4B-0E8A5593F94FQ41954269-9F62EE3F-6A3E-4CAF-BA49-56F98871D31EQ42490579-F2834D74-FAEC-4E43-8050-C6EEEF2AE1E5Q42801859-E7852BD5-583D-4510-A578-6B74197999BCQ42807084-B374ADBA-9D58-464E-900B-7DE9C8BDF370Q42807633-EA25CACB-7335-4972-BE8B-AB5633FFF1CBQ42816004-AC3B73DE-19C7-4E59-B1A5-A19565932A51Q42817645-D43B5D49-C56F-4D5E-BD8B-B1B37948F1E8Q42823528-CC19187D-2FB7-4D5E-BAE6-F4F1043835ADQ42824590-588BE04D-FFF4-4D84-BB51-A6A870155906Q42826316-5888DA30-4CE6-4C8E-B5D9-4E54D89C2F07Q42828122-99B7688E-DE34-4FF2-958D-4B22EF244C16
P2860
Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@en
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@nl
type
label
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@en
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@nl
prefLabel
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@en
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@nl
P2093
P2860
P1433
P1476
Botulinum C3 exoenzyme blocks ...... ed by bombesin and endothelin.
@en
P2093
P2860
P304
P356
10.1016/0014-5793(94)01148-6
P407
P577
1994-11-01T00:00:00Z