Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek.
about
Linking human diseases to animal models using ontology-based phenotype annotationSfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signalingWnt/beta-catenin signaling and small molecule inhibitorsDkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesisThe extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivoBulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cellsMutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt SignalingClusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathwayDkk-1 inhibits intestinal epithelial cell migration by attenuating directional polarization of leading edge cellsLrp6 is required for convergent extension during Xenopus gastrulation.The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.The WNT signaling antagonist Dickkopf-1 directs lineage commitment and promotes survival of the preimplantation embryo.Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.The role of glypicans in Wnt inhibitory factor-1 activity and the structural basis of Wif1's effects on Wnt and Hedgehog signaling.Mapping of Wnt, frizzled, and Wnt inhibitor gene expression domains in the avian otic primordium.High throughput identification of monoclonal antibodies to membrane bound and secreted proteins using yeast and phage display.Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling.R-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryos.Wnt signaling interacts with bmp and edn1 to regulate dorsal-ventral patterning and growth of the craniofacial skeleton.Dual-color dual-focus line-scanning FCS for quantitative analysis of receptor-ligand interactions in living specimensCell polarity: The missing link in skeletal morphogenesis?Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanismRac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.The functions and possible significance of Kremen as the gatekeeper of Wnt signalling in development and pathology.From individual Wnt pathways towards a Wnt signalling network.Dhrs3 protein attenuates retinoic acid signaling and is required for early embryonic patterningShared gene expression patterns in mesenchymal progenitors derived from lung and epidermis in pulmonary arterial hypertension: identifying key pathways in pulmonary vascular disease.Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway.Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo.Potential cross-talk between (pro)renin receptors and Wnt/frizzled receptors in cardiovascular and renal disorders.Boning up on glypicans--opportunities for new insights into bone biology.Integration of anterior neural plate patterning and morphogenesis by the Wnt signaling pathway.Striatal cholinergic interneurons in isolated generalized dystonia-rationale and perspectives for stem cell-derived cellular models.Heading forwards: anterior visceral endoderm migration in patterning the mouse embryo.Vertebrate nervous system posteriorization: Grading the function of Wnt signaling.Rationale for targeting the Wnt signalling modulator Dickkopf-1 for oncology.Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3.Hematopoietic cyclooxygenase-2 deficiency increases adipose tissue inflammation and adiposity in obesity.Jarid2 Coordinates Nanog Expression and PCP/Wnt Signaling Required for Efficient ESC Differentiation and Early Embryo Development.
P2860
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P2860
Dickkopf-1 regulates gastrulation movements by coordinated modulation of Wnt/beta catenin and Wnt/PCP activities, through interaction with the Dally-like homolog Knypek.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@en
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@nl
type
label
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@en
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@nl
prefLabel
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@en
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@nl
P2093
P2860
P356
P1433
P1476
Dickkopf-1 regulates gastrulat ...... the Dally-like homolog Knypek.
@en
P2093
Christof Niehrs
Luca Caneparo
Masasumi Tada
Nicole Staudt
Olga Kazanskaya
Reiner Ahrendt
Ya-Lin Huang
P2860
P304
P356
10.1101/GAD.406007
P577
2007-02-01T00:00:00Z