TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. - Wikidata - awgldk - TriplyDB

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.

http://www.wikidata.org/entity/Q42857077

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Pharmacological inhibitors of TRPV4 channels reduce cytokine production, restore endothelial function and increase survival in septic mice Nitrite therapy improves survival postexposure to chlorine gas Novel regulators of endothelial barrier function An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness.Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury Mechanotransduction via TRPV4 regulates inflammation and differentiation in fetal mouse distal lung epithelial cells.Respiratory syncytial virus infection increases chlorine-induced airway hyperresponsiveness Transient receptor potential channels in the vasculature.Genetic deficit of KCa 3.1 channels protects against pulmonary circulatory collapse induced by TRPV4 channel activation.Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4.TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis.Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury.Transient receptor potential (TRP) channels as a therapeutic target for intervention of respiratory effects and lethality from phosgene.Activation of TRPV4 Regulates Respiration through Indirect Activation of Bronchopulmonary Sensory Neurons.Baicalin exerts protective effects against lipopolysaccharide-induced acute lung injury by regulating the crosstalk between the CX3CL1-CX3CR1 axis and NF-κB pathway in CX3CL1-knockout mice.Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells.The pathophysiology of pulmonary hypertension in left heart disease.TRP functions in the broncho-pulmonary system.Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.Fluid-induced lung injury-role of TRPV4 channels.The role of stretch-activated ion channels in acute respiratory distress syndrome: finally a new target?Mustard vesicant-induced lung injury: Advances in therapy.Emerging roles of calcium-activated K channels and TRPV4 channels in lung oedema and pulmonary circulatory collapse.Nitrite therapy prevents chlorine gas toxicity in rabbits.CD36 mediates H2O2-induced calcium influx in lung microvascular endothelial cells.The Role of Transient Receptor Potential Vanilloid 4 in Pulmonary Inflammatory Diseases.A Curious Case of Inhalation Fever Caused by Synthetic Cannabinoid.Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury.Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells.Permeability and calcium signaling in lung endothelium: unpack the box….Nitric Oxide-Dependent Feedback Loop Regulates Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Cooperativity and Endothelial Function in Small Pulmonary Arteries.Cytokine-Ion Channel Interactions in Pulmonary Inflammation.Ion channels of the lung and their role in disease pathogenesis.Instillation of Hyaluronan Reverses Acid Instillation Injury to the Mammalian Blood Gas Barrier.Δ9-Tetrahydrocannabinol changes the brain lipidome and transcriptome differentially in the adolescent and the adult.TRPA1: Acrolein meets its target.Mechanosensitive transient receptor potential vanilloid 4 regulates Dermatophagoides farinae-induced airway remodeling via 2 distinct pathways modulating matrix synthesis and degradation.TRPV4: an exciting new target to promote alveolocapillary barrier function.The role of placenta growth factor in the hyperoxia-induced acute lung injury in an animal model.

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P2860

TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury.

http://www.wikidata.org/entity/Q42857077

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2014 nî lūn-bûn

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2014年論文

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2014年論文

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2014年论文

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name

TRPV4 inhibition counteracts e ...... lly induced acute lung injury.

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AJPLUNG.00065.2014

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American Journal of Physiology - Lung Cellular and Molecular Physiology

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TRPV4 inhibition counteracts e ...... ally induced acute lung injury

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P2093

Aiwei Sui

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Boyi Liu

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Guosen Ye

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Heather B Bradshaw

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Hilary S Eidam

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Kevin S Thorneloe

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Melanie M Kaelberer

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Mui Cheung

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Robert N Willette

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Sadis Matalon

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P2860

An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor

TopHat: discovering splice junctions with RNA-Seq

Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures.

A FAAH-regulated class of N-acyl taurines that activates TRP ion channels

Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models

Postexposure administration of a {beta}2-agonist decreases chlorine-induced airway hyperreactivity in mice

Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling

TRPA1 is a major oxidant sensor in murine airway sensory neurons

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2

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Satyanarayana Achanta

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