Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation.
about
Cdk1 targets Srs2 to complete synthesis-dependent strand annealing and to promote recombinational repairAn overview of Cdk1-controlled targets and processesBLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repairRTEL1 maintains genomic stability by suppressing homologous recombinationThe RecQ DNA helicases in DNA repairDNA end resection: many nucleases make light workMaintaining Genome Stability in Defiance of Mitotic DNA DamageDNA dynamics during early double-strand break processing revealed by non-intrusive imaging of living cellsNej1 recruits the Srs2 helicase to DNA double-strand breaks and supports repair by a single-strand annealing-like mechanism.Mre11 and Ku regulation of double-strand break repair by gene conversion and break-induced replication.Sen1p contributes to genomic integrity by regulating expression of ribonucleotide reductase 1 (RNR1) in Saccharomyces cerevisiae.A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair.Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes.Srs2 mediates PCNA-SUMO-dependent inhibition of DNA repair synthesis.Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA.Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break endsThe CDK-activating kinase (CAK) Csk1 is required for normal levels of homologous recombination and resistance to DNA damage in fission yeast.Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats.Mechanism of the ATP-dependent DNA end-resection machinery from Saccharomyces cerevisiae.DNA end resection by Dna2-Sgs1-RPA and its stimulation by Top3-Rmi1 and Mre11-Rad50-Xrs2.Srs2: the "Odd-Job Man" in DNA repair.End resection at double-strand breaks: mechanism and regulation.An mre11 mutation that promotes telomere recombination and an efficient bypass of senescence.Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cellsSgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.RPA coordinates DNA end resection and prevents formation of DNA hairpins.Tryptophan-Dependent Control of Colony Formation After DNA Damage via Sea3-Regulated TORC1 Signaling in Saccharomyces cerevisiae.Srs2 and Mus81-Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates.DNA End Resection: Nucleases Team Up with the Right Partners to Initiate Homologous RecombinationThe human F-Box DNA helicase FBH1 faces Saccharomyces cerevisiae Srs2 and postreplication repair pathway roles.Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction.Repair Pathway Choices and Consequences at the Double-Strand BreakImpaired resection of meiotic double-strand breaks channels repair to nonhomologous end joining in Caenorhabditis elegans.The Saccharomyces cerevisiae Esc2 and Smc5-6 proteins promote sister chromatid junction-mediated intra-S repair.MRE11 complex links RECQ5 helicase to sites of DNA damage.Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption.A transient α-helical molecular recognition element in the disordered N-terminus of the Sgs1 helicase is critical for chromosome stability and binding of Top3/Rmi1.Srs2 prevents Rad51 filament formation by repetitive motion on DNA.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.
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Srs2 and Sgs1 DNA helicases associate with Mre11 in different subcomplexes following checkpoint activation and CDK1-mediated Srs2 phosphorylation.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@en
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@nl
type
label
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@en
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@nl
prefLabel
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@en
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@nl
P2860
P50
P1476
Srs2 and Sgs1 DNA helicases as ...... mediated Srs2 phosphorylation.
@en
P2093
Giulio Maffioletti
Walter Carotenuto
P2860
P304
P356
10.1128/MCB.25.13.5738-5751.2005
P407
P577
2005-07-01T00:00:00Z