A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. - Wikidata - awgldk - TriplyDB

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.

http://www.wikidata.org/entity/Q42966589

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Case Characterization, Clinical Features and Risk Factors in Drug-Induced Liver Injury The Latin American DILI Registry Experience: A Successful Ongoing Collaborative Strategic Initiative Drug-Induced Liver Injury Network Causality Assessment: Criteria and Experience in the United States The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?Update on Advances in Research on Idiosyncratic Drug-Induced Liver Injury MicroRNAs in Drug-induced Liver Injury Impact of New Genomic Technologies on Understanding Adverse Drug Reactions New approaches for predicting T cell-mediated drug reactions: A role for inducible and potentially preventable autoimmunity New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response.Idiosyncratic adverse drug reactions: current concepts Mechanisms of drug-induced liver injury Contributions of nonhematopoietic cells and mediators to immune responses: implications for immunotoxicology Pharmacogenomics of adverse drug reactions The challenges, advantages and future of phenome-wide association studies Pathogenesis of idiosyncratic drug-induced liver injury and clinical perspectives.Fever, rash, and systemic symptoms: understanding the role of virus and HLA in severe cutaneous drug allergy.The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity Progress in understanding the genomic basis for adverse drug reactions: a comprehensive review and focus on the role of ethnicity Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps)HLA alleles influence the clinical signature of amoxicillin-clavulanate hepatotoxicity Mechanism of isoniazid‐induced hepatotoxicity: then and now Drug-induced liver injury: recent advances in diagnosis and risk assessment.Human leucocyte antigen-adverse drug reaction associations: from a perspective of ethnicity.Drug-induced liver injury: Advances in mechanistic understanding that will inform risk management.Hepatotoxicity induced by coxibs: how concerned should we be?Pharmacogenomics of off-target adverse drug reactions.Genotyping for severe drug hypersensitivity.Developing pharmacogenetic evidence throughout clinical development.Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis Mechanisms of drug-induced liver injury: from bedside to bench.Genome-wide association study identifies susceptibility loci for IgA nephropathy.In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury.Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients Ongoing challenges in pharmacovigilance.Causality assessment for suspected DILI during clinical phases of drug development T cell-mediated hypersensitivity reactions to drugs Pharmacogenomics: will the promise be fulfilled?

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P2860

A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.

http://www.wikidata.org/entity/Q42966589

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

A genome-wide study identifies ...... iracoxib-related liver injury.

@en

A genome-wide study identifies ...... iracoxib-related liver injury.

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type

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A genome-wide study identifies ...... iracoxib-related liver injury.

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A genome-wide study identifies ...... iracoxib-related liver injury.

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A genome-wide study identifies ...... iracoxib-related liver injury.

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A genome-wide study identifies ...... iracoxib-related liver injury.

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Nature Genetics

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A genome-wide study identifies ...... iracoxib-related liver injury.

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Charles A Paulding

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Elisabeth Leroy

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Fan Yang

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Joanne Meyer

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Jonathan B Singer

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Lloyd Klickstein

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Steve Lewitzky

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Timothy M Wright

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Xiaojun Zhao

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P2860

PLINK: a tool set for whole-genome association and population-based linkage analyses

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial

Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

Medical genetics: a marker for Stevens-Johnson syndrome

HLA association of amoxicillin-clavulanate--induced hepatitis

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.

Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir.

Drug-related hepatotoxicity.

Lumiracoxib in the management of osteoarthritis and acute pain.

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10.1038/NG.632

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