Mechanisms of drug-induced liver injury: from bedside to bench.
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The Need for Biomarkers in Diagnosis and Prognosis of Drug-Induced Liver Disease: Does Metabolomics Have Any Role?Biomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory scienceCellular imaging: a key phenotypic screening strategy for predictive toxicologyNovel in vitro and mathematical models for the prediction of chemical toxicityEngineering liverDrug-induced hepatotoxicity: metabolic, genetic and immunological basisDrug allergy: causes and desensitizationIdentification of novel translational urinary biomarkers for acetaminophen-induced acute liver injury using proteomic profiling in miceProfiles of serum cytokines in acute drug-induced liver injury and their prognostic significanceDrug-induced liver injury: recent advances in diagnosis and risk assessment.Acute liver injury in a patient with alcohol dependence: a case resembling autoimmune hepatitis or drug-induced liver injuryExploration of Biomarkers for Amoxicillin/Clavulanate-Induced Liver Injury: Multi-Omics Approaches.Long-term culture of human liver tissue with advanced hepatic functions.Relationship between characteristics of medications and drug-induced liver disease phenotype and outcome.The Effects of Melatonin on Elevated Liver Enzymes during Statin Treatment.Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis.In vitro platforms for evaluating liver toxicity.Pregnane X receptor and drug-induced liver injury.An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjectsProteomic profiling in incubation medium of mouse, rat and human precision-cut liver slices for biomarker detection regarding acute drug-induced liver injury.Liraglutide-induced autoimmune hepatitisModerate activation of IKK2-NF-kB in unstressed adult mouse liver induces cytoprotective genes and lipogenesis without apparent signs of inflammation or fibrosis.Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicityCytotoxic Synergy Between Cytokines and NSAIDs Associated With Idiosyncratic Hepatotoxicity Is Driven by Mitogen-Activated Protein KinasesAneuploidy as a mechanism for stress-induced liver adaptation.Identification of Identical Transcript Changes in Liver and Whole Blood during Acetaminophen Toxicity.Detection of nanolevel drug metabolites in an organotypic culture of primary human hepatocytes and porcine hepatocytes with special reference to a two-compartment model.Parkin and mitofusins reciprocally regulate mitophagy and mitochondrial spheroid formation.Blood transcript immune signatures distinguish a subset of people with elevated serum ALT from others given acetaminophenGap junction inhibition prevents drug-induced liver toxicity and fulminant hepatic failure.A case of acute liver failure due to etodolacA Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity.Serum proteomic profiling in patients with drug-induced liver injury.DILI: New Insights into Diagnosis and Management.Subtoxic Alterations in Hepatocyte-Derived Exosomes: An Early Step in Drug-Induced Liver Injury?Ferulic acid attenuated acetaminophen-induced hepatotoxicity though down-regulating the cytochrome P 2E1 and inhibiting toll-like receptor 4 signaling-mediated inflammation in mice.Metronidazole induced liver injury: a rare immune mediated drug reaction.Efficacy and safety of danoprevir-ritonavir plus peginterferon alfa-2a-ribavirin in hepatitis C virus genotype 1 prior null responders.Idiosyncratic Drug-Induced Liver Injury (IDILI): Potential Mechanisms and Predictive Assays.
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Mechanisms of drug-induced liver injury: from bedside to bench.
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
Mechanisms of drug-induced liver injury: from bedside to bench.
@ast
Mechanisms of drug-induced liver injury: from bedside to bench.
@en
Mechanisms of drug-induced liver injury: from bedside to bench.
@nl
type
label
Mechanisms of drug-induced liver injury: from bedside to bench.
@ast
Mechanisms of drug-induced liver injury: from bedside to bench.
@en
Mechanisms of drug-induced liver injury: from bedside to bench.
@nl
prefLabel
Mechanisms of drug-induced liver injury: from bedside to bench.
@ast
Mechanisms of drug-induced liver injury: from bedside to bench.
@en
Mechanisms of drug-induced liver injury: from bedside to bench.
@nl
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P356
P1476
Mechanisms of drug-induced liver injury: from bedside to bench.
@en
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Robert J Fontana
Shannan Tujios
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P2888
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P356
10.1038/NRGASTRO.2011.22
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P577
2011-03-08T00:00:00Z