Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. - Wikidata - awgldk - TriplyDB

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

http://www.wikidata.org/entity/Q42966822

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A Systematic Review of Carcinogenic Outcomes and Potential Mechanisms from Exposure to 2,4-D and MCPA in the Environment Occupational safety and health, green chemistry, and sustainability: a review of areas of convergence The next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directions Induced Pluripotent Stem Cell Models to Enable In Vitro Models for Screening in the Central Nervous System The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling Triclosan: A Widespread Environmental Toxicant with Many Biological Effects Phenotypically anchored transcriptome profiling of developmental exposure to the antimicrobial agent, triclosan, reveals hepatotoxicity in embryonic zebrafish Addressing human variability in next-generation human health risk assessments of environmental chemicals t4 workshop report: Pathways of Toxicity Editor's Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.Incorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.Prediction of in vivo developmental toxicity of all-trans-retinoic acid based on in vitro toxicity data and in silico physiologically based kinetic modeling.Predictive model of rat reproductive toxicity from ToxCast high throughput screening.Development and Validation of a Computational Model for Androgen Receptor Activity Consideration of dosimetry in evaluation of ToxCast™ data.A framework for the next generation of risk science.DemQSAR: predicting human volume of distribution and clearance of drugs.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Development of screening tools for the interpretation of chemical biomonitoring data Endocrine disruptors and asthma-associated chemicals in consumer products Triclosan exposure and allergic sensitization in Norwegian children Chemical compounds from anthropogenic environment and immune evasion mechanisms: potential interactions A framework incorporating the impact of exposure scenarios and application conditions on risk assessment of chemicals applied to skin.Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.Application of physiologically based pharmacokinetic models in chemical risk assessment.Toxicokinetic Triage for Environmental Chemicals.Cutting Edge PBPK Models and Analyses: Providing the Basis for Future Modeling Efforts and Bridges to Emerging Toxicology Paradigms Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing.Physiological fidelity or model parsimony? The relative performance of reverse-toxicokinetic modeling approaches.Intake to production ratio: a measure of exposure intimacy for manufactured chemicals.In vitro screening for population variability in toxicity of pesticide-containing mixtures Integration of Life-Stage Physiologically Based Pharmacokinetic Models with Adverse Outcome Pathways and Environmental Exposure Models to Screen for Environmental Hazards.FutureTox: building the road for 21st century toxicology and risk assessment practices Toward toxicity testing of nanomaterials in the 21st century: a paradigm for moving forward.Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results.Mode of action and dose-response framework analysis for receptor-mediated toxicity: The aryl hydrocarbon receptor as a case study.Critical consideration of the multiplicity of experimental and organismic determinants of pyrethroid neurotoxicity: a proof of concept.In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.Risk assessment in the 21st century: roadmap and matrix.

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Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

http://www.wikidata.org/entity/Q42966822

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Incorporating human dosimetry ...... t in vitro toxicity screening.

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Incorporating human dosimetry ...... t in vitro toxicity screening.

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Toxicological Sciences

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Incorporating human dosimetry ...... ut in vitro toxicity screening

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Barbara A Wetmore

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Cornelia M Smith

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David J Dix

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Frank Boellmann

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Harvey J Clewell

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Keith A Houck

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Mark A Sochaski

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Robert J Kavlock

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Stephen S Ferguson

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P2860

REACHing for chemical safety.

Simulation and prediction of in vivo drug metabolism in human populations from in vitro data

The Simcyp population-based ADME simulator

Metabolism and kinetics of bisphenol a in humans at low doses following oral administration

Toward a new U.S. chemicals policy: rebuilding the foundation to advance new science, green chemistry, and environmental health.

The integration of data on physico-chemical properties, in vitro-derived toxicity data and physiologically based kinetic and dynamic as modelling a tool in hazard and risk assessment. A commentary.

An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.

The toxicity data landscape for environmental chemicals.

Clearance concepts in pharmacokinetics.

The ToxCast program for prioritizing toxicity testing of environmental chemicals.

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348-358

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10.1093/TOXSCI/KFQ220

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2

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117

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Russell S. Thomas

Edward L. LeCluyse

John F. Wambaugh

Matthew T Martin

Richard S. Judson

Melvin E. Andersen

Daniel M Rotroff

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2010-07-16T00:00:00Z

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45271637

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20639261

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6280841

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