In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.
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The next generation of risk assessment multiyear study - highlights of findings, applications to risk assessment, and future directionsCancer Biology, Toxicology and Alternative Methods Development Go Hand-in-HandA Novel Drug-Mouse Phenotypic Similarity Method Detects Molecular Determinants of Drug EffectsReference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.Model-based contextualization of in vitro toxicity data quantitatively predicts in vivo drug response in patients.Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial CellsIn Silico Study of In Vitro GPCR Assays by QSAR Modeling.Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin.Human pluripotent stem cell-derived neural constructs for predicting neural toxicity.Combination of multiple neural crest migration assays to identify environmental toxicants from a proof-of-concept chemical library.A human liver microphysiology platform for investigating physiology, drug safety, and disease modelsMoving Toward Integrating Gene Expression Profiling Into High-Throughput Testing: A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray CompendiumThe use of mode of action information in risk assessment: quantitative key events/dose-response framework for modeling the dose-response for key events.In vitro micro-physiological models for translational immunology.Predicting organ toxicity using in vitro bioactivity data and chemical structure.Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis.Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development.Predictions of bisphenol A hepatic clearance in the isolated perfused rat liver (IPRL): impact of albumin binding and of co-administration with naproxen.Evolving the Principles and Practice of Validation for New Alternative Approaches to Toxicity Testing.The role of high-throughput screening in ecotoxicology and engineered nanomaterials.Development of estrogen receptor beta binding prediction model using large sets of chemicals.Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.Neural organoids for disease phenotyping, drug screening and developmental biology studies.Workshop of Scandinavian Society for Cell Toxicology 25-27 September 2013 in Denmark.In silico cancer research towards 3R.OPERA models for predicting physicochemical properties and environmental fate endpoints.
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P2860
In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
In vitro and modelling approac ...... tion Agency ToxCast programme.
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type
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In vitro and modelling approac ...... tion Agency ToxCast programme.
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In vitro and modelling approac ...... tion Agency ToxCast programme.
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P2093
P2860
P50
P356
P1476
In vitro and modelling approac ...... tion Agency ToxCast programme.
@en
P2093
Matt Martin
Nisha Sipes
Thomas Knudsen
P2860
P356
10.1111/BCPT.12239
P577
2014-04-22T00:00:00Z