A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
about
Structure-function analysis of the 3' stem-loop of hepatitis C virus genomic RNA and its role in viral RNA replicationThe phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition3' nontranslated RNA signals required for replication of hepatitis C virus RNAcis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genomeStructural characterization of the highly conserved 98-base sequence at the 3' end of HCV RNA genome and the complementary sequence located at the 5' end of the replicative viral strandCommon and unique features of viral RNA-dependent polymerasesStructural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with RibonucleotidesSelection of 3'-template bases and initiating nucleotides by hepatitis C virus NS5B RNA-dependent RNA polymeraseMechanism of de novo initiation by the hepatitis C virus RNA-dependent RNA polymerase: role of divalent metals.Recombinant viral RdRps can initiate RNA synthesis from circular templates.Hepatitis C Virus RNA Synthesis in a Cell-Free System Isolated from Replicon-Containing Hepatoma CellsIn vitro RNA replication directed by replicase complexes isolated from the subgenomic replicon cells of hepatitis C virusDinucleotide Analogues as Novel Inhibitors of RNA-Dependent RNA Polymerase of Hepatitis C VirusIdentification of a C-Terminal Regulatory Motif in Hepatitis C Virus RNA-Dependent RNA Polymerase: Structural and Biochemical AnalysisDe Novo Synthesis of Negative-Strand RNA by Dengue Virus RNA-Dependent RNA Polymerase In Vitro: Nucleotide, Primer, and Template ParametersMolecular Mechanism of a Thumb Domain Hepatitis C Virus Nonnucleoside RNA-Dependent RNA Polymerase InhibitorGeneral Catalytic Deficiency of Hepatitis C Virus RNA Polymerase with an S282T Mutation and Mutually Exclusive Resistance towards 2'-Modified Nucleotide AnaloguesMechanism of Activation of -D-2'-Deoxy-2'-Fluoro-2'-C-Methylcytidine and Inhibition of Hepatitis C Virus NS5B RNA PolymeraseCrystal Structure of the Dengue Virus RNA-Dependent RNA Polymerase Catalytic Domain at 1.85-Angstrom ResolutionPyrophosphorolytic Excision of Nonobligate Chain Terminators by Hepatitis C Virus NS5B PolymeraseInhibition of Hepatitis C Virus (HCV) RNA Polymerase by DNA Aptamers: Mechanism of Inhibition of In Vitro RNA Synthesis and Effect on HCV-Infected CellsResistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor1,5-Benzodiazepines, a Novel Class of Hepatitis C Virus Polymerase Nonnucleoside InhibitorsThe Hepatitis C Virus NS5A Stimulates NS5B During In Vitro RNA Synthesis in a Template Specific MannerMechanism of Hepatitis C Virus RNA Polymerase Inhibition with DihydroxypyrimidinesCrystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymeraseCrystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleftFurther Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA SynthesisNoncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus 6 from De Novo Initiation to ElongationStructures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contactsStructure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNAViral replication. Structural basis for RNA replication by the hepatitis C virus polymeraseAssembly, purification, and pre-steady-state kinetic analysis of active RNA-dependent RNA polymerase elongation complexA Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae FamilyPerturbation in the conserved methyltransferase-polymerase interface of flavivirus NS5 differentially affects polymerase initiation and elongationUnravelling hepatitis C virus replication from genome to functionInitiation of RNA synthesis by the hepatitis C virus RNA-dependent RNA polymerase is affected by the structure of the RNA template.Mechanisms of activity and inhibition of the hepatitis C virus RNA-dependent RNA polymerase.Molecular simulations illuminate the role of regulatory components of the RNA polymerase from the hepatitis C virus in influencing protein structure and dynamicsNew Therapies for Hepatitis C Virus Infection.
P2860
Q24540195-D8AECA42-833B-4617-AF56-894AB5EEB592Q24542010-71A56194-69E0-4D5C-A715-9A6373C979EEQ24550606-C6D057A7-570F-4899-A493-2C13CDBEF65EQ24563876-0D8AD3AC-E674-4F91-B727-99ED444D9B87Q24802132-B7CE697D-5A13-4631-91C8-84F97ED90D97Q27001753-1679AA48-88E4-4CCB-8462-014A8E5647AFQ27472850-CAC0C590-4B93-46EF-9C9D-F208F718530DQ27472883-B01E2C47-0865-41E5-993B-494F97A6B20DQ27472913-71C4A2A1-D6B9-4914-8403-FBD6A6E45C5BQ27472979-6FD92364-9A47-4EE4-832D-0E219B83159DQ27473087-0BE50444-1947-461A-BF2D-3D063B2DB9E2Q27473097-F2DDF0B9-A68E-4BBC-9DDF-C1FFA20A81A4Q27477688-D2F71650-DF03-41EF-BA41-3368EC9F379CQ27477707-C7E66857-ED5E-4C37-9B14-D0043A6E4536Q27477711-59A291F4-D64F-4A29-BB5B-DFDBF144ED6EQ27477757-0BB7043E-243A-40F1-BED6-FBD0827E518CQ27477760-605FF42B-9050-4429-A216-643DFA584435Q27478073-7758FB4C-AA51-47F6-8747-547DA886EE4AQ27480349-BFC14BEA-CB26-49E6-A5CF-83BAA1EBAD78Q27480921-15C39AE4-1741-4906-AEC4-A490F5EC93AAQ27486247-8C2A8713-82B7-4A87-AD00-FAF06F50475CQ27486873-B23AFF77-2229-4BB7-9DBD-F07B223CB831Q27487390-B61FB2F3-EE2F-4CBD-B649-DE49B540D3F6Q27488841-56DF4ACC-61E9-45EA-AB9E-09C9802BC0A4Q27490954-6A413B31-A63F-4AEF-8D6C-CCB30976B1F3Q27635562-0341DFFE-56CA-4035-B80D-59DDB2BD5E7FQ27643088-3AF8F43F-B677-444C-BE6D-5A53552BCBA8Q27664120-8207CB0D-A8ED-412F-BA97-0F3E457F0E6FQ27676480-B0CB75D7-1EF1-4A4E-98E0-3AB121E9CD31Q27678100-D1744EFA-B6BD-4819-8B44-16461BBB1BFBQ27678475-B28FF806-1391-4DDE-A819-EC9F483B4430Q27697984-D099CCCF-8CCB-40A8-BC52-8B7EFC44D01DQ28258867-3EAE15C0-AA8D-462F-BEE9-DE1556931209Q28647618-8B67DE38-5E9F-446B-9A89-CDCAD7E6FA3FQ28651848-A9349798-407C-4CC8-9152-8F1C435DCC78Q29620056-0D4617BE-C62A-44CA-85B7-4D1B72C4D3C1Q30317019-3642ED82-0AAD-42F4-8BE6-8C3F1A76AD6CQ30318760-761A1059-D744-4202-BF3D-2AB21EB2E05AQ30431492-7783D6B8-46D5-4B45-8F13-B3A440293FE9Q33560181-D03BC458-8325-4755-88A7-54A609478DD5
P2860
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@en
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@nl
type
label
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@en
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@nl
prefLabel
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@en
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@nl
P2093
P356
P1433
P1476
A novel mechanism to ensure terminal initiation by hepatitis C virus NS5B polymerase.
@en
P2093
Cameron CE
P356
10.1006/VIRO.2001.0948
P407
P577
2001-06-01T00:00:00Z