Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
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E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repressionE2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phaseNetwork calisthenics: control of E2F dynamics in cell cycle entryFeedback loops and reciprocal regulation: recurring motifs in the systems biology of the cell cycleControl of cell cycle transcription during G1 and S phasesAtypical E2F repressors and activators coordinate placental developmentE2F8 is essential for polyploidization in mammalian cellsCanonical and atypical E2Fs regulate the mammalian endocycleE2F7 represses a network of oscillating cell cycle genes to control S-phase progressionKelch Repeat and BTB Domain Containing Protein 5 (Kbtbd5) Regulates Skeletal Muscle Myogenesis through the E2F1-DP1 ComplexIdentification of a Low-Frequency Missense Variant in E2F Transcription Factor 7 Associated with Colorectal Cancer Risk In A Chinese PopulationAtypical E2F activity restrains APC/CCCS52A2 function obligatory for endocycle onsetLive-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control.Context-dependent requirement for dE2F during oncogenic proliferationE2F8 is a Potential Therapeutic Target for Hepatocellular CarcinomaAG1478 inhibits the migration and invasion of cisplatin-resistant human lung adenocarcinoma cells via the cell cycle regulation by matrix metalloproteinase-9Inactivation of Rb and E2f8 synergizes to trigger stressed DNA replication during erythroid terminal differentiation.Integrated transcriptome and binding sites analysis implicates E2F in the regulation of self-renewal in human pluripotent stem cells.G1 arrest and differentiation can occur independently of Rb family function.S phase-coupled E2f1 destruction ensures homeostasis in proliferating tissues.A Type VI secretion system encoding locus is required for Bordetella bronchiseptica immunomodulation and persistence in vivo.E2F6 associates with BRG1 in transcriptional regulation.Atypical E2F activity coordinates PHR1 photolyase gene transcription with endoreduplication onsetMouse development with a single E2F activator.E2F in vivo binding specificity: comparison of consensus versus nonconsensus binding sites.Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4.Emerging roles of E2Fs in cancer: an exit from cell cycle controlCharacterization of ENU-induced Mutations in Red Blood Cell Structural Proteins.Targeting Rb inactivation in cancers by synthetic lethality.The rb pathway and cancer therapeuticsHox and a newly identified E2F co-repress cell death in Caenorhabditis elegansThe role of the E2F transcription factor family in UV-induced apoptosis.Concomitant inactivation of Rb and E2f8 in hematopoietic stem cells synergizes to induce severe anemiaMature T cell responses are controlled by microRNA-142.The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.E2F8 as a Novel Therapeutic Target for Lung CancerRecruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.Structural insights into the DNA-binding specificity of E2F family transcription factors
P2860
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P2860
Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Synergistic function of E2F7 a ...... val and embryonic development.
@en
Synergistic function of E2F7 a ...... val and embryonic development.
@nl
type
label
Synergistic function of E2F7 a ...... val and embryonic development.
@en
Synergistic function of E2F7 a ...... val and embryonic development.
@nl
prefLabel
Synergistic function of E2F7 a ...... val and embryonic development.
@en
Synergistic function of E2F7 a ...... val and embryonic development.
@nl
P2093
P2860
P1433
P1476
Synergistic function of E2F7 a ...... ival and embryonic development
@en
P2093
Alain de Bruin
Chang-Gong Liu
Faye Gordon
Grant Comstock
Gustavo Leone
Hasan Siddiqui
Hui-Zi Chen
P2860
P356
10.1016/J.DEVCEL.2007.10.017
P407
P577
2008-01-01T00:00:00Z