about
Cognitive-Behavioural Therapy for Inflammatory Bowel Disease: 24-Month Data from a Randomised Controlled Trial.Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia.Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil.Identifying the Ion Channels Responsible for Signaling Gastro-Intestinal Based PainA novel role for TRPM8 in visceral afferent function.Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression.Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.Cognitive-behavioural therapy has no effect on disease activity but improves quality of life in subgroups of patients with inflammatory bowel disease: a pilot randomised controlled trialSelective role for TRPV4 ion channels in visceral sensory pathways.The ion channel TRPA1 is required for normal mechanosensation and is modulated by algesic stimuliTRP channels: new targets for visceral pain.Immune activation in irritable bowel syndrome: can neuroimmune interactions explain symptoms?Opioidergic effects on enteric and sensory nerves in the lower GI tract: basic mechanisms and clinical implications.Fluoxetine for Maintenance of Remission and to Improve Quality of Life in Patients with Crohn's Disease: a Pilot Randomized Placebo-Controlled Trial.Colonic immune cells in irritable bowel syndrome: A systematic review and meta-analysis.Sensory neuro-immune interactions differ between irritable bowel syndrome subtypes.Increased κ-opioid receptor expression and function during chronic visceral hypersensitivity.TRPA1 contributes to specific mechanically activated currents and sensory neuron mechanical hypersensitivity.Aldehyde dehydrogenase, nitric oxide synthase and superoxide in ex vivo nitrate tolerance in rat aorta.Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses.Involvement of metabotropic glutamate 5 receptor in visceral pain.Activation of colo-rectal high-threshold afferent nerves by Interleukin-2 is tetrodotoxin-sensitive and upregulated in a mouse model of chronic visceral hypersensitivity.Longitudinal analysis indicates symptom severity influences immune profile in irritable bowel syndrome.Acute colitis chronically alters immune infiltration mechanisms and sensory neuro-immune interactions.Repeated administration of the substituted amphetamine p-methoxyamphetamine produces reductions in cortical 5-HT transporter binding but not 5-HT content, unlike 3,4-methylenedioxyamethamphetamine.Immune derived opioidergic inhibition of viscerosensory afferents is decreased in Irritable Bowel Syndrome patients.CO-EXPRESSION OF μ AND ∂ OPIOID RECEPTORS BY MOUSE COLONIC NOCICEPTORS.Colonic migrating motor complexes are inhibited in acute tri-nitro benzene sulphonic acid colitis.Innervation of the Gastrointestinal Tract by Spinal and Vagal Afferent NervesSprouting of colonic afferent central terminals and increased spinal mitogen-activated protein kinase expression in a mouse model of chronic visceral hypersensitivityThe Hot Mustard Receptor's Role in Gut Motor FunctionImmuno-PET of innate immune markers CD11b and IL-1β detect inflammation in murine colitisAdvances in Imaging Specific Mediators of Inflammatory Bowel DiseaseSleeping in on pancreatic cancer pain: Schwann cell secreted IL-6 pushes snooze on the pain alarmEffect of Fecal Microbiota Transplantation on 8-Week Remission in Patients With Ulcerative Colitis: A Randomized Clinical TrialAcute Colitis Drives Tolerance by Persistently Altering the Epithelial Barrier and Innate and Adaptive Immunity
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
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name
Patrick Hughes
@ast
Patrick Hughes
@en
Patrick Hughes
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Patrick Hughes
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Patrick Hughes
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type
label
Patrick Hughes
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Patrick Hughes
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Patrick Hughes
@es
Patrick Hughes
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Patrick Hughes
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prefLabel
Patrick Hughes
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Patrick Hughes
@en
Patrick Hughes
@es
Patrick Hughes
@nl
Patrick Hughes
@sl
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P1153
7403234337
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P2798
P31
P496
0000-0001-7324-3626