Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
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Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinineNavigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's DiseaseDesign and synthesis of a bivalent ligand to explore the putative heterodimerization of the mu opioid receptor and the chemokine receptor CCR5.Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease.AChE Inhibition-based Multi-target-directed Ligands, a Novel Pharmacological Approach for the Symptomatic and Disease-modifying Therapy of Alzheimer's Disease.Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease.A novel bivalent HIV-1 entry inhibitor reveals fundamental differences in CCR5-μ-opioid receptor interactions between human astroglia and microglia.Stimulation, protection and regeneration of dopaminergic neurons by 9-methyl-β-carboline: a new anti-Parkinson drug?Stabilizers of neuronal and mitochondrial calcium cycling as a strategy for developing a medicine for Alzheimer's disease.Multi-Target Directed Drugs: A Modern Approach for Design of New Drugs for the treatment of Alzheimer's Disease.Synthesis and antitumor activity of novel N-substituted tetrahydro-β-carboline-imidazolium salt derivatives.Synthesis of new isoxazoline derivatives from harmine and evaluation of their anti-Alzheimer, anti-cancer and anti-inflammatory activities.Novel multitarget-directed tacrine derivatives as potential candidates for the treatment of Alzheimer's disease.The Role of Hippocampal 5HT3 Receptors in Harmaline-Induced Memory Deficit.Tacrine, Trolox and Tryptoline as Lead Compounds for the Design and Synthesis of Multi-target Agents for Alzheimer's Disease Therapy.Elaborate ligand-based modeling coupled with QSAR analysis and in silico screening reveal new potent acetylcholinesterase inhibitors.The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon.Determination of Structural Requirements of N-Substituted Tetrahydro-β-Carboline Imidazolium Salt Derivatives Using in Silico Approaches for Designing MEK-1 Inhibitors.1-Benzyl-1,2,3,4-tetrahydro-β-carboline as channel blocker of N-methyl-D-aspartate receptors.
P2860
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P2860
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
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2010年學術文章
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name
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@en
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@nl
type
label
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@en
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@nl
prefLabel
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@en
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@nl
P2093
P356
P1476
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
@en
P2093
Bernhard Wünsch
Dirk Schepmann
Friedemann Gaube
Jochen Lehmann
Jörg Heilmann
Kai-Uwe Schmidtke
Thomas Winckler
Yvonne Rook
P304
P356
10.1021/JM1000024
P407
P577
2010-05-01T00:00:00Z