Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells. - Wikidata - awgldk - TriplyDB

Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.

Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.

http://www.wikidata.org/entity/Q43130050

about

Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells.Development and characterization of human-induced pluripotent stem cell-derived cholangiocytes.A Convenient and Efficient Method to Enrich and Maintain Highly Proliferative Human Fetal Liver Stem Cells Novel surface markers directed against adult human gallbladder Cross Talk Between GH-Regulated Transcription Factors HNF6 and CUX2 in Adult Mouse Liver.Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion.Transplantation of hESC-derived hepatocytes protects mice from liver injury.Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation Notch Signaling Coordinates Progenitor Cell-Mediated Biliary Regeneration Following Partial Hepatectomy.Role of β-catenin in development of bile ducts.Cell sources for in vitro human liver cell culture models.Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas.Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver.Longitudinal in vivo bioimaging of hepatocyte transcription factor activity following cholestatic liver injury in mice Potential of human induced pluripotent stem cells in studies of liver disease.Treatment of hepatitis C in difficult-to-treat patients.Current strategies to generate mature human induced pluripotent stem cells derived cholangiocytes and future applications.Expression kinetics of hepatic progenitor markers in cellular models of human liver development recapitulating hepatocyte and biliary cell fate commitment.Efficient and Controlled Generation of 2D and 3D Bile Duct Tissue from Human Pluripotent Stem Cell-Derived Spheroids.Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice.Pluripotent stem cells for disease modeling and drug screening: new perspectives for treatment of cystic fibrosis?Challenges on the road to a multicellular bioartificial liver.Regenerative Medicine and the Biliary Tree.Architecture in 3D cell culture: An essential feature for in vitro toxicology.Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Perfused Three-Dimensional Multicompartment Bioreactor.Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks.Single-cell RNA-Seq analysis reveals dynamic trajectories during mouse liver development.Alagille syndrome: Genetics and Functional Models.Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.Development and characterization of cholangioids from normal and diseased human cholangiocytes as an in vitro model to study primary sclerosing cholangitis.Rapid Screening of the Endodermal Differentiation Potential of Human Pluripotent Stem Cells.A single-cell transcriptomic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation.Directed differentiation of cholangiocytes from human pluripotent stem cells.[Human pluripotent stem cells and liver disorders].Src kinase inhibition reduces inflammatory and cytoskeletal changes in ΔF508 human cholangiocytes and improves cystic fibrosis transmembrane conductance regulator correctors efficacy.Adenylyl cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in polycystic liver disease.Complex bile duct network formation within liver decellularized extracellular matrix hydrogels

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P2860

Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells.

http://www.wikidata.org/entity/Q43130050

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

@zh-cn

2014年学术文章

@zh-hans

2014年学术文章

@zh-my

2014年学术文章

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2014年學術文章

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2014年學術文章

@zh-hant

name

Generation of functional chola ...... t stem cells and HepaRG cells.

@en

Generation of functional chola ...... t stem cells and HepaRG cells.

@nl

type

label

Generation of functional chola ...... t stem cells and HepaRG cells.

@en

Generation of functional chola ...... t stem cells and HepaRG cells.

@nl

prefLabel

Generation of functional chola ...... t stem cells and HepaRG cells.

@en

Generation of functional chola ...... t stem cells and HepaRG cells.

@nl

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Generation of functional chola ...... nt stem cells and HepaRG cells

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P2093

Anne Corlu

http://www.w3.org/2001/XMLSchema#string

Anne Weber

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Aurélien Raveux

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Christophe Desterke

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Hélène Dubois-Pot-Schneider

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Noushin Dianat

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Philippe Leclerc

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P2860

Human pluripotent stem cells for modelling human liver diseases and cell therapy

Suppression of C/EBPalpha expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression

The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis

The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis

Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9

Loss of inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis.

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.

Heterogeneity of the intrahepatic biliary epithelium

Infection of a human hepatoma cell line by hepatitis B virus.

Foxa1 and Foxa2 regulate bile duct development in mice.

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10.1002/HEP.27165

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2

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Laurent Combettes

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2014-06-20T00:00:00Z

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