Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development. - Wikidata - awgldk - TriplyDB

Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.

Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.

http://www.wikidata.org/entity/Q43182598

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Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?Intracellular Molecular Differences in Aldosterone- Compared to Cortisol-Secreting Adrenal Cortical Adenomas Adrenocortical zonation, renewal, and remodeling Toying with fate: Redirecting the differentiation of adrenocortical progenitor cells into gonadal-like tissue Diagnostic and prognostic features in adrenocortical carcinoma: a single institution case series and review of the literature Analysis of the role of Igf2 in adrenal tumour development in transgenic mouse models Upregulated JAG1 enhances cell proliferation in adrenocortical carcinoma Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice Wnt signaling inhibits adrenal steroidogenesis by cell-autonomous and non-cell-autonomous mechanisms.Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R.Understanding primary aldosteronism: impact of next generation sequencing and expression profiling.Emerging therapy for adrenocortical carcinoma.Pediatric adrenocortical tumors: what they can tell us on adrenal development and comparison with adult adrenal tumors.Therapy of adrenocortical cancer: present and future.Current and emerging therapies for advanced adrenocortical carcinoma.PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumors.Adrenocortical neoplasia: evolving concepts in tumorigenesis with an emphasis on adrenal cortical carcinoma variants.Molecular and Cellular Mechanisms of Aldosterone Producing Adenoma Development MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.Adrenocortical stem and progenitor cells: implications for adrenocortical carcinoma Towards an understanding of the role of p53 in adrenocortical carcinogenesis.Animal models of adrenocortical tumorigenesis Development of adrenal cortex zonation.Combined transcriptome studies identify AFF3 as a mediator of the oncogenic effects of β-catenin in adrenocortical carcinoma.GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker Adrenocortical stem and progenitor cells: unifying model of two proposed origins.Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin Regulation of the adrenocortical stem cell niche: implications for disease GATA factors in endocrine neoplasia Adrenocortical Carcinoma: Current Therapeutic State-of-the-Art.Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells.Mouse models of adrenocortical tumors.Activating mutations in CTNNB1 in aldosterone producing adenomas.Inhibition of the Tcf/beta-catenin complex increases apoptosis and impairs adrenocortical tumor cell proliferation and adrenal steroidogenesis.Molecular Heterogeneity in Aldosterone-Producing Adenomas cAMP/PKA signaling defects in tumors: genetics and tissue-specific pluripotential cell-derived lesions in human and mouse.Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.The cAMP pathway and the control of adrenocortical development and growth

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Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.

http://www.wikidata.org/entity/Q43182598

description

2010 nî lūn-bûn

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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2010年學術文章

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name

Constitutive beta-catenin acti ...... es adrenal cancer development.

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Constitutive beta-catenin acti ...... es adrenal cancer development.

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type

label

Constitutive beta-catenin acti ...... es adrenal cancer development.

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Constitutive beta-catenin acti ...... es adrenal cancer development.

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prefLabel

Constitutive beta-catenin acti ...... es adrenal cancer development.

@en

Constitutive beta-catenin acti ...... es adrenal cancer development.

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Human Molecular Genetics

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Constitutive beta-catenin acti ...... tes adrenal cancer development

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Annabel Berthon

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Anne-Marie Lefrançois-Martinez

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Antoine Martinez

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Christelle Damon-Soubeyrand

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Cyrille de Joussineau

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Estelle Louiset

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Frédérique Tissier

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Isabelle Sahut-Barnola

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Mark M Taketo

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Pierre Val

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The Hallmarks of Cancer

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

SF-1 a key player in the development and differentiation of steroidogenic tissues

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Transcription factors GATA-4 and GATA-6 in human adrenocortical tumors

Wnt-4 deficiency alters mouse adrenal cortex function, reducing aldosterone production

Apc tumor suppressor gene is the "zonation-keeper" of mouse liver

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

Wnt signaling: a common theme in animal development

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

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1561-1576

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10.1093/HMG/DDQ029

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8

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19

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Jérome Bertherat

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41165884

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20106872

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