Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity. - Wikidata - awgldk - TriplyDB

Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.

Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.

http://www.wikidata.org/entity/Q43196382

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Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium?Role of prostaglandins in neuroinflammatory and neurodegenerative diseases Therapeutic potential of monoacylglycerol lipase inhibitors Neuronal Gene Targets of NF-κB and Their Dysregulation in Alzheimer's Disease Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD Inhibition of soluble tumor necrosis factor ameliorates synaptic alterations and Ca2+ dysregulation in aged rats Growth factors in synaptic function.Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid.A role for cyclooxygenase-1 in beta-amyloid-induced neuroinflammation.Omega-3 fatty acids and dementia.Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice.Tracking neuroinflammation in Alzheimer's disease: the role of positron emission tomography imaging.Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening.Probing the biology of Alzheimer's disease in mice.Obovatol improves cognitive functions in animal models for Alzheimer's disease.Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease The Potential for Plant Derivatives against Acrylamide Neurotoxicity.Neuroprotective effects of treadmill exercise on BDNF and PI3-K/Akt signaling pathway in the cortex of transgenic mice model of Alzheimer's disease.Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease.Neuroinflammation and memory: the role of prostaglandins Extended results of the Alzheimer's disease anti-inflammatory prevention trial.Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.Synaptic and extrasynaptic NMDA receptors differentially modulate neuronal cyclooxygenase-2 function, lipid peroxidation, and neuroprotection.Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration.Chemical Biology, Molecular Mechanism and Clinical Perspective of γ-Secretase Modulators in Alzheimer's Disease Indomethacin-loaded lipid-core nanocapsules reduce the damage triggered by Aβ1-42 in Alzheimer's disease models.Endoplasmic reticulum stress-mediated hippocampal neuron apoptosis involved in diabetic cognitive impairment.Acetate reduces PGE2 release and modulates phospholipase and cyclooxygenase levels in neuroglia stimulated with lipopolysaccharide A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease.Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer's disease model mice.Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease.Botanical phenolics and brain health CHF5074, a novel gamma-secretase modulator, attenuates brain beta-amyloid pathology and learning deficit in a mouse model of Alzheimer's disease.Prostaglandin I2 upregulates the expression of anterior pharynx-defective-1α and anterior pharynx-defective-1β in amyloid precursor protein/presenilin 1 transgenic mice.The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.An update on the efficacy of non-steroidal anti-inflammatory drugs in Alzheimer's disease.Untangling the Web: Toxic and Protective Effects of Neuroinflammation and PGE2 Signaling in Alzheimer's Disease.Antioxidant gene therapy against neuronal cell death.

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Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.

http://www.wikidata.org/entity/Q43196382

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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name

Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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type

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Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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Cyclooxygenase-2 inhibition im ...... emory and synaptic plasticity.

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Agnes Simonyi

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Agnieszka Falinska

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Giselle P Lim

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Grace Y Sun

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Greg Cole

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James Cleary

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Karen H Ashe

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Kimberly Panizzon

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Linda A Kotilinek

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Linda H Younkin

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

Cyclooxygenase-independent actions of cyclooxygenase inhibitors

Reduced incidence of AD with NSAID but not H2 receptor antagonists: the Cache County Study

Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production

Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

A specific amyloid-beta protein assembly in the brain impairs memory

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651-664

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scholarly article

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10.1093/BRAIN/AWN008

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P433

Pt 3

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131

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Sylvain E Lesné

Michael J Rowan

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2008-03-01T00:00:00Z

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5560295

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18292081

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2628581

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