Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis. - Wikidata - awgldk - TriplyDB

Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.

Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.

http://www.wikidata.org/entity/Q43228860

about

Cutting the brakes on hematopoietic regeneration by blocking TGFβ to limit chemotherapy-induced myelosuppression Ineffective erythropoiesis in β -thalassemia Aconitase regulation of erythropoiesis correlates with a novel licensing function in erythropoietin-induced ERK signaling.Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain Defining an EPOR- regulated transcriptome for primary progenitors, including Tnfr-sf13c as a novel mediator of EPO- dependent erythroblast formation Protein kinase D-HDAC5 signaling regulates erythropoiesis and contributes to erythropoietin cross-talk with GATA1 Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression.Erythropoietin down-regulates stem cell factor receptor (Kit) expression in the leukemic proerythroblast: role of Lyn kinase Oncostatin M receptor β and cysteine/histidine-rich 1 are biomarkers of the response to erythropoietin in hemodialysis patients.Future alternative therapies for β-thalassemia.Advances in understanding the pathogenesis of primary familial and congenital polycythaemia Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.Essential role for focal adhesion kinase in regulating stress hematopoiesis.Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities.During EPO or anemia challenge, erythroid progenitor cells transit through a selectively expandable proerythroblast pool Erythropoiesis: development and differentiation.Enu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele.Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice Emerging EPO and EPO receptor regulators and signal transducers.Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.BMP4, SCF, and hypoxia cooperatively regulate the expansion of murine stress erythroid progenitors.Erythropoietin modulation of podocalyxin and a proposed erythroblast niche.Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-3-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity Microglial integrity is maintained by erythropoietin through integration of Akt and its substrates of glycogen synthase kinase-3beta, beta-catenin, and nuclear factor-kappaB.EPO modulation of cell-cycle regulatory genes, and cell division, in primary bone marrow erythroblasts Spry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor.STAT5 requires the N-domain to maintain hematopoietic stem cell repopulating function and appropriate lymphoid-myeloid lineage output.A unique role for Stat5 in recovery from acute anemia.Erythropoietin-directed erythropoiesis depends on serpin inhibition of erythroblast lysosomal cathepsins.EPO receptor circuits for primary erythroblast survival Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2.The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.Targeting erythroblast-specific apoptosis in experimental anemia Erythropoietin and oxidative stress.

P2860

Q26745695-B0C42CE5-D78E-44D3-B1DB-9EFA206A6B0F Q26830255-571F34FB-E439-4C30-B29E-7E2ECAA1772F Q27323049-ACFE5B94-B369-473F-99E9-6E7F24067DFA Q28509188-D924EF62-B22A-4638-97B2-FE548165D144 Q28544690-F5A317EF-030B-4DD2-A2CB-20A3E50C10DE Q28727049-6A4D4CEB-03A4-44CF-950E-3118958591D1 Q30416330-D6A141F2-223C-4484-90F8-D2EC267B6D48 Q33288270-6F988F6A-0481-4F4A-A5DF-D3D003E5C57F Q33459267-544CB889-3E48-414D-8BAE-B5151AAE4D05 Q33625452-C5CD1533-7B7B-4024-B40F-FD66BD3C1238 Q33659678-285DCD1D-2C06-450D-8FEE-0518A02B4477 Q33828925-6C636DAE-626C-485A-AB6B-E6706B339D47 Q33961430-FAE87A44-D9A7-4A57-A4D1-413AE17546C4 Q34293299-F25C033A-CD72-4F4C-AE20-A73036D9E0A9 Q34360298-2AD9BE17-403A-4CEF-8B71-AF4BA2102314 Q34411804-DBCD5E6F-4C26-4E51-9C96-4E5E4C67EDE0 Q34450491-B0EB2604-76D4-4D94-8446-F8D33AFB35C4 Q34649958-E1528963-E02F-443A-8768-975A4247E158 Q35005652-C8FAFF53-6C75-4537-BCAD-A8E13DB86B5C Q35370181-8758A34B-8A84-4757-9FA2-E07D82892E86 Q35692391-EED327B0-94BC-41A2-937C-34731702606C Q35750349-BEAC1391-8961-40C4-863E-A5FE1B9F1355 Q35828707-097A948B-C307-4849-BC37-75697375D0D9 Q35900969-8EEFF313-31EF-45BC-AF66-80046BE7067D Q35950357-0C0260F3-472E-41E5-A9FE-ACED7E8DB884 Q36002858-7125F9B7-B0C7-4E5B-8E25-F9B64A34B1B7 Q36007623-D0792055-FA5D-4DF0-8854-96F95B0346D7 Q36015223-19619CBD-A393-4306-B915-713302D781AD Q36122227-97C0D317-6C11-4C01-962C-DF4434EEE291 Q36258552-7DA8497D-194F-47CD-9E16-F242CEE28A22 Q36411137-706A40D3-DE6B-4189-B96D-C0F6DB9C07EC Q36603518-34EE0DC8-1F73-47A2-8CB2-490C7C1D78F2 Q36677326-586A4F0F-1FC5-47C3-A236-E59C03322502 Q36740470-8BCEA49F-E708-48CC-B79B-E29AED451A52 Q36745518-87FBE077-6BFB-4B27-B96B-F28D8246F06C Q36787514-20406394-873D-49FB-AF6B-A333203B016F Q36787528-89E3270E-8D43-4ED0-8E46-53A0B97C004F Q36836455-991B9302-6BA6-4CEF-9232-F4AD10187B06 Q36914540-11A5DEB2-CD6E-457A-BEFA-30F928BD7D68 Q36944477-2F688979-1751-4B60-A11C-22419D9CF8EE

P2860

Signals for stress erythropoiesis are integrated via an erythropoietin receptor-phosphotyrosine-343-Stat5 axis.

http://www.wikidata.org/entity/Q43228860

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年学术文章

@wuu

2006年学术文章

@zh

2006年学术文章

@zh-cn

2006年学术文章

@zh-hans

2006年学术文章

@zh-my

2006年学术文章

@zh-sg

2006年學術文章

@yue

2006年學術文章

@zh-hant

name

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@en

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@nl

type

label

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@en

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@nl

prefLabel

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@en

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@nl

P1433

Q43228860-FCA52A9B-F695-49B7-992E-E59C0A771760

P1476

Q43228860-DDC1CD25-902A-48FF-B5BC-83F25A98C9B1

P2093

Q43228860-42F506D1-A96C-4BC4-B5BF-DF9975AAB348

Q43228860-5A8D5AA3-39A2-452B-AD00-6BE4BFAADC1F

Q43228860-64DCF633-5B16-4C50-9F0D-6AFDADAED4BB

Q43228860-B93925DF-343E-48F8-BD08-944317B57610

Q43228860-E17D53EE-CC3B-4D69-9DCB-2C2144D8E4EC

Q43228860-E694E293-2DE5-4944-9879-9AB105390557

P2860

Q43228860-049421FF-2E60-4698-A9CF-60053363A634

Q43228860-05357E8B-75F0-4ED8-8473-AE1E194A6AF3

Q43228860-095B9CB7-B7CC-4906-8C44-0C50A79BD0A1

Q43228860-09EACD7C-9318-406C-9BA2-922178A97B44

Q43228860-0C3FC7FD-C7FA-44E0-8DCF-2FDC47190A41

Q43228860-0CA0445B-7F8B-4323-ACF0-D2CE4F608CB4

Q43228860-1106F0A8-FB5C-47E6-9DD0-4084AD6A734A

Q43228860-194EBE97-ABF5-425C-BA5F-00B233C4A6EA

Q43228860-1B59B9DC-1C0A-4505-B4B4-C1AFB97ACB7F

Q43228860-201D26F5-5038-4D86-9CDC-155183461D08

P304

Q43228860-7D0BF500-251C-4523-8100-20C3E5E1DA9C

P31

Q43228860-896F1223-EFA6-404F-8FAD-BB21EFAC1D37

P356

Q43228860-6910153A-9AFB-44B8-87EC-88871E7592C4

P407

Q43228860-9436C134-F3F4-45B3-9CBF-8C7068B360B6

P433

Q43228860-01C19364-65A5-4185-93A9-136D39F10151

P478

Q43228860-30C663CD-C6DA-4D6B-9F05-9A2BBDC3EFC6

P577

Q43228860-3B765AC8-E76C-438F-BBE5-196C25279EEE

P698

Q43228860-BE597CD3-E053-496D-966B-ABF48BD8FE18

P921

Q43228860-2EE24CBE-2113-4C55-A90E-076FF7D8E6A0

P932

Q43228860-6D886467-1DCE-414A-9A00-7B0B423BB4FB

P356

P1433

Journal of Clinical Investigation

P1476

Signals for stress erythropoie ...... hosphotyrosine-343-Stat5 axis.

@en

P2093

Bethany Cuetara

http://www.w3.org/2001/XMLSchema#string

Don M Wojchowski

http://www.w3.org/2001/XMLSchema#string

Madhu P Menon

http://www.w3.org/2001/XMLSchema#string

Oleg Bogachev

http://www.w3.org/2001/XMLSchema#string

Olga Bogacheva

http://www.w3.org/2001/XMLSchema#string

Vinit Karur

http://www.w3.org/2001/XMLSchema#string

P2860

The distal region and receptor tyrosines of the Epo receptor are non-essential for in vivo erythropoiesis

Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway

Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

The SH2 inositol 5-phosphatase Ship1 is recruited in an SH2-dependent manner to the erythropoietin receptor

Tyrosine-phosphorylated SOCS-3 inhibits STAT activation but binds to p120 RasGAP and activates Ras

A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis

P304

683-694

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1172/JCI25227

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

116

http://www.w3.org/2001/XMLSchema#string

P577

2006-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

16511603

http://www.w3.org/2001/XMLSchema#string

P921

P932

1386105

http://www.w3.org/2001/XMLSchema#string