Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice. - Wikidata - awgldk - TriplyDB

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.

http://www.wikidata.org/entity/Q43238371

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Oxidative Stress in the Healthy and Wounded Hepatocyte: A Cellular Organelles Perspective Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences Reactive oxygen species and fibrosis: further evidence of a significant liaison Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease Chronic Activation of Hepatic Nrf2 Has No Major Effect on Fatty Acid and Glucose Metabolism in Adult Mice Nrf2 enhances cholangiocyte expansion in Pten-deficient livers High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2.Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.NF-E2-related factor 1 (Nrf1) serves as a novel regulator of hepatic lipid metabolism through regulation of the Lipin1 and PGC-1β genes Nrf2 affects the efficiency of mitochondrial fatty acid oxidation.Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice Butyrate-producing probiotics reduce nonalcoholic fatty liver disease progression in rats: new insight into the probiotics for the gut-liver axis.The role of the antioxidant and longevity-promoting Nrf2 pathway in metabolic regulation.Endoplasmic reticulum stress and the unfolded protein response in nonalcoholic fatty liver disease.Myeloid deletion of nuclear factor erythroid 2-related factor 2 increases atherosclerosis and liver injury.Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine.New player on an old field; the keap1/Nrf2 pathway as a target for treatment of type 2 diabetes and metabolic syndrome.Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet.Role of the Nrf2-ARE pathway in liver diseases Nrf2: a potential target for new therapeutics in liver disease.Drug metabolism alterations in nonalcoholic fatty liver disease Nrf2 deletion causes "benign" simple steatosis to develop into nonalcoholic steatohepatitis in mice fed a high-fat diet New insights from rodent models of fatty liver disease Fatty acids and the endoplasmic reticulum in nonalcoholic fatty liver disease Nuclear factor (erythroid-derived 2)-like-2 factor (Nrf2), a key regulator of the antioxidant response to protect against atherosclerosis and nonalcoholic steatohepatitis.Role of Nrf2 in chronic liver disease.OSAS-related inflammatory mechanisms of liver injury in nonalcoholic fatty liver disease.The Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism.Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet.NADPH Oxidases in Chronic Liver Diseases p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.Nature and Implications of Oxidative and Nitrosative Stresses in Autoimmune Hepatitis.Naturally Occurring Nrf2 Activators: Potential in Treatment of Liver Injury.Yinchen Linggui Zhugan Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats by Regulating the Nrf2/ARE Signaling Pathway Rosiglitazone attenuates age- and diet-associated nonalcoholic steatohepatitis in male low-density lipoprotein receptor knockout mice.Role of Nrf2 in the alteration of cholesterol and bile acid metabolism-related gene expression by dietary cholesterol in high fat-fed mice.Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH.Non-Alcoholic Fatty Liver Disease.Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2.

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Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice.

http://www.wikidata.org/entity/Q43238371

description

2009 nî lūn-bûn

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2009年の論文

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年学术文章

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2009年學術文章

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2009年學術文章

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name

Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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type

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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AJPGI.00296.2009

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American Journal of Physiology - Gastrointestinal and Liver Physiology

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Deletion of nuclear factor-E2- ...... ional steatohepatitis in mice.

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Akira Nakahara

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Eiji Warabi

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Hirokazu Sugimoto

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Ichinosuke Hyodo

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Junichi Shoda

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Kazunori Ishige

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Keiko Taguchi

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Kosuke Okada

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Masayuki Yamamoto

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Tetsuro Ishii

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P2860

Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Genetic evidence that small maf proteins are essential for the activation of antioxidant response element-dependent genes.

An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen

PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress

Steatohepatitis: a tale of two "hits"?

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

The natural history of nonalcoholic fatty liver disease: a population-based cohort study

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Steatohepatitis