Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.
about
Next-generation antimicrobials: from chemical biology to first-in-class drugsDiverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma bruceiA static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes.Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaignIdentification of novel compounds inhibiting chikungunya virus-induced cell death by high throughput screening of a kinase inhibitor libraryBiological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathwayNew compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.The establishment of in vitro culture and drug screening systems for a newly isolated strain of Trypanosoma equiperdum.Synthesis of antitrypanosomal 1,2-dioxane derivatives based on a natural product scaffold.A quantitative high throughput assay for identifying gametocytocidal compoundsWhole-organism high-throughput screening against Trypanosoma brucei brucei.Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatosEstablishment of ATP-based luciferase viability assay in 96-well plate for Trypanosoma congolense.A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlueN¹,N¹-Dimethyl-N³-(3-(trifluoromethyl)phenethyl)propane-1,3-diamine, a new lead for the treatment of human African trypanosomiasis.Computer-aided discovery of Trypanosoma brucei RNA-editing terminal uridylyl transferase 2 inhibitors.Drug discovery for human African trypanosomiasis: identification of novel scaffolds by the newly developed HTS SYBR Green assay for Trypanosoma brucei.Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasitesIdentification and Characterization of FTY720 for the Treatment of Human African Trypanosomiasis.Metabolomics guides rational development of a simplified cell culture medium for drug screening against Trypanosoma brucei.Luminescent multiplex viability assay for Trypanosoma brucei gambiense.Anti-trypanosome effects of nutritional supplements and vitamin D3: in vitro and in vivo efficacy against Trypanosoma brucei bruceiBloodstream form pre-adaptation to the tsetse fly in Trypanosoma brucei.Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis.High-throughput chemical screening for antivirulence developmental phenotypes in Trypanosoma brucei.In vitro screening test using Leishmania promastigotes stably expressing mCherry protein.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.Drugs for Neglected Diseases initiative model of drug development for neglected diseases: current status and future challenges.In vitro drug susceptibility of two strains of the wildlife trypanosome, Trypanosoma copemani: A comparison with Trypanosoma cruziCytoprotection by omega-3 fatty acids as a therapeutic drug vehicle when combined with nephrotoxic drugs in an intravenous emulsion: Effects on intraglomerular mesangial cellsScreening a Natural Product-Based Library against Kinetoplastid Parasites.An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate.Monovinyl sulfone β-cyclodextrin. A flexible drug carrier system.The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processingMetabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilideSynthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agentsWilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni
P2860
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P2860
Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Development of an Alamar Blue ...... i bloodstream form strain 427.
@en
Development of an Alamar Blue ...... i bloodstream form strain 427.
@nl
type
label
Development of an Alamar Blue ...... i bloodstream form strain 427.
@en
Development of an Alamar Blue ...... i bloodstream form strain 427.
@nl
prefLabel
Development of an Alamar Blue ...... i bloodstream form strain 427.
@en
Development of an Alamar Blue ...... i bloodstream form strain 427.
@nl
P1476
Development of an Alamar Blue ...... ei bloodstream form strain 427
@en
P2093
Melissa L Sykes
P304
P356
10.4269/AJTMH.2009.09-0015
P407
P577
2009-10-01T00:00:00Z