I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.
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Recent developments in using mechanistic cardiac modelling for drug safety evaluationDeterminants of beat-to-beat variability of repolarization duration in the canine ventricular myocyte: a computational analysisPopulation of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisationLate sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.Beat-to-beat cycle length variability of spontaneously beating guinea pig sinoatrial cells: relative contributions of the membrane and calcium clocks.Application of stochastic phenomenological modelling to cell-to-cell and beat-to-beat electrophysiological variability in cardiac tissueCardiac ventricular repolarization reserve: a principle for understanding drug-related proarrhythmic risk.A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis.Comparison of the IKr blockers moxifloxacin, dofetilide and E-4031 in five screening models of pro-arrhythmia reveals lack of specificity of isolated cardiomyocytesQT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESC Working Group on Cardiac Cellular EleElectrical storm: recent pathophysiological insights and therapeutic consequences.Role of abnormal repolarization in the mechanism of cardiac arrhythmia.Circadian pattern of short-term variability of the QT-interval in primary prevention ICD patients - EU-CERT-ICD methodological pilot study.Ca2+-activated Cl- current is antiarrhythmic by reducing both spatial and temporal heterogeneity of cardiac repolarization.An in silico canine cardiac midmyocardial action potential duration model as a tool for early drug safety assessment.Combined inhibition of key potassium currents has different effects on cardiac repolarization reserve and arrhythmia susceptibility in dogs and rabbits.Contribution of ion currents to beat-to-beat variability of action potential duration in canine ventricular myocytes.Relation between QT interval variability and muscle sympathetic nerve activity in normal subjects.Beat-to-beat variability of cardiac action potential duration: underlying mechanism and clinical implications.Oxidative shift in tissue redox potential increases beat-to-beat variability of action potential duration.Arrhythmogenic Mechanisms in Heart Failure: Linking β-Adrenergic Stimulation, Stretch, and CalciumAn Augmented Negative Force-Frequency Relationship and Slowed Mechanical Restitution Are Associated With Increased Susceptibility to Drug-Induced Torsade de Pointes Arrhythmias in the Chronic Atrioventricular Block DogRelation between QT interval variability and cardiac sympathetic activity in hypertension
P2860
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P2860
I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
I(Ks) restricts excessive beat ...... renergic receptor stimulation.
@en
type
label
I(Ks) restricts excessive beat ...... renergic receptor stimulation.
@en
prefLabel
I(Ks) restricts excessive beat ...... renergic receptor stimulation.
@en
P2093
P1476
I(Ks) restricts excessive beat ...... drenergic receptor stimulation
@en
P2093
Chris E Pollard
Harry J G M Crijns
Jean-Pierre Valentin
Najah Abi-Gerges
Paul G A Volders
P304
P356
10.1016/J.YJMCC.2009.08.033
P577
2009-09-08T00:00:00Z