Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain.

Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain.

Item
http://www.wikidata.org/entity/Q43287762
Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug developmentDistinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice.Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanismsIsoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer diseaseThe isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.Identification and Epigenetic Analysis of a Maternally Imprinted Gene Qpct.Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse modelsCommon variants in QPCT gene confer risk of schizophrenia in the Han Chinese population.
P2860

Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain.

Item
http://www.wikidata.org/entity/Q43287762
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Developmental expression and s ...... aminyl cyclase in mouse brain.
@en
Developmental expression and s ...... aminyl cyclase in mouse brain.
@nl
type
label
Developmental expression and s ...... aminyl cyclase in mouse brain.
@en
Developmental expression and s ...... aminyl cyclase in mouse brain.
@nl
prefLabel
Developmental expression and s ...... aminyl cyclase in mouse brain.
@en
Developmental expression and s ...... aminyl cyclase in mouse brain.
@nl
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Developmental expression and s ...... aminyl cyclase in mouse brain.
@en
P2093
P304
P31
P356
10.1016/J.IJDEVNEU.2009.08.007
P433
P478
P50
P577
P5875
P698