about
Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus.Learning improvement after PI3K activation correlates with de novo formation of functional small spinesAnti-inflammatory activity of a honey flavonoid extract on lipopolysaccharide-activated N13 microglial cells.Centrosomal aggregates and Golgi fragmentation disrupt vesicular trafficking of DAT.Regional difference in inflammatory response to LPS-injection in the brain: role of microglia cell density.Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer's mice hippocampus.Cellular environment facilitates protein accumulation in aged rat hippocampus.Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer mAge and meloxicam attenuate the ischemia/reperfusion-induced down-regulation in the NMDA receptor genes.Extracellular amyloid-beta and cytotoxic glial activation induce significant entorhinal neuron loss in young PS1(M146L)/APP(751SL) mice.Prevalence between different alpha subunits performing the benzodiazepine binding sites in native heterologous GABA(A) receptors containing the alpha2 subunit.Age-related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects.Rat hippocampal GABAergic molecular markers are differentially affected by ageing.Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease.Age-related differences in the dynamics of hippocampal proteasome recovery.Absence of association between delta and gamma2 subunits in native GABA(A) receptors from rat brain.Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons.Distribution of NADPH-diaphorase and nitric oxide synthase reactivity in the central nervous system of the goldfish (Carassius auratus).Native gamma-aminobutyric acid type A receptors from rat hippocampus, containing both alpha 1 and alpha 5 subunits, exhibit a single benzodiazepine binding site with alpha 5 pharmacological properties.Molecular heterogeneity of the type I GABAA/benzodiazepine receptor complex.Calretinin interneurons are early targets of extracellular amyloid-beta pathology in PS1/AbetaPP Alzheimer mice hippocampus.Absence of modifications of the pharmacological properties of the GABAA receptor complex during aging, as assessed in 3- and 24-month-old rat cerebral cortex.Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice.Comparative autoradiographic distribution of central omega (benzodiazepine) modulatory site subtypes with high, intermediate and low affinity for zolpidem and alpidem.Regional differences in the enhancement by GABA of [3H]zolpidem binding to omega 1 sites in rat brain membranes and sections.Pharmacological properties of the GABA(A) receptor complex from brain regions of (hypoemotional) Roman high- and (hyperemotional) low-avoidance rats.Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection.Rapid PCR-mediated synthesis of competitor molecules for accurate quantification of beta(2) GABA(A) receptor subunit mRNA.Expression of GABA(A) receptor subunit mRNAs by layer V pyramidal cells of the rat primary visual cortex.Pharmacologic characterization of GABAA/benzodiazepine receptor in rat hippocampus during aging.Molecular and pharmacological characterization of native cortical gamma-aminobutyric acidA receptors containing both alpha1 and alpha3 subunits.Age-related modifications on the GABAA receptor binding properties from Wistar rat prefrontal cortex.Aging-related subunit expression changes of the GABAA receptor in the rat hippocampus.Kainate receptor subunits expressed in single cultured hippocampal neurons: molecular and functional variants by RNA editing.Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.Postnatal development of the α1 containing GABAA receptor subunit in rat hippocampusHeterogeneity in the allosteric interaction between the gamma-aminobutyric acid (GABA) binding site and three different benzodiazepine binding sites of the GABAA/benzodiazepine receptor complex in the rat nervous systemMolecular characterization of type I GABAA receptor complex from rat cerebral cortex and hippocampusAging-associated changes in the pharmacological properties of the benzodiazepine (omega) receptor isotypes in the rat hippocampus
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Diego Ruano
@ast
Diego Ruano
@en
Diego Ruano
@es
Diego Ruano
@nl
Diego Ruano
@sl
type
label
Diego Ruano
@ast
Diego Ruano
@en
Diego Ruano
@es
Diego Ruano
@nl
Diego Ruano
@sl
prefLabel
Diego Ruano
@ast
Diego Ruano
@en
Diego Ruano
@es
Diego Ruano
@nl
Diego Ruano
@sl
P1053
I-4471-2014
P106
P21
P31
P3829
P496
0000-0001-6131-3033